上海莱士 002252 公司章程 上海莱士血液制品股份有限公司 章程 （2025年7月修订） 2025年7月 1 上海莱士 002252 公司章程 上海莱士血液制品股份有限公司 章 程 目 录 第一章 总则 第二章 经营宗旨和范围 第三章 股份 第四章 股东和股东大会 第五章 董事会 第六章 总经理及其他高级管理人员 1 第一节 股份发行 第二节 股份增减和回购 第三节 股份转让 第一节 股东 第二节 股东大会的一般规定 第三节 股东大会的召集 第四节 股东大会的提案与通知 第五节 股东大会的召开 第六节 股东大会的表决和决议 第一节 董事 第二节 董事会 上海莱士 002252 公司章程 第七章 监事会 第八章 财务会计制度、利润分配和审计 第九章 通知与公告 第十章 合并、分立、增资、减资、解散和清算 第十一章 修改章程 第十二章 附则 2 第一节 监事 第二节 监事会 第一节 财务会计制度 第二节 内部审计 第三节 会计师事务所的聘任 第一节 通知 第二节 公告 第一节 合并、分立、增资和减资 第二节 解散和清算 英文名称：Shanghai RAAS Blood Products Co., Ltd. 第 ...

证券代码：002252 证券简称：上海莱士 公告编号：2025-054 上海莱士血液制品股份有限公司 4、会议召开的日期、时间： 现场会议召开时间为：2025 年 7 月 31 日（星期四）14:00； 网络投票时间为：2025 年 7 月 31 日（星期四）； 其中，通过深圳证券交易所交易系统进行网络投票的具体时间为：2025 年 7 月 31 日（星期四）的交易时间，即 9:15－9:25，9:30－11:30，13:00－15:00；通 过深圳证券交易所互联网投票系统投票的具体时间为：2025 年 7 月 31 日（星期 四）9:15 至 15:00 期间的任意时间。 关于召开2025年第二次临时股东大会的通知 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 上海莱士血液制品股份有限公司（"公司"）于2025年7月15日召开第六届董 事会第十二次（临时）会议，审议通过了《关于召集2025年第二次临时股东大会 的议案》，会议定于2025年7月31日（星期四）14:00召开公司2025年第二次临时股 东大会，现将本次股东大会的有关事项通知如下： 一、召开会议 ...

证券代码：002252 证券简称：上海莱士 公告编号：2025-052 上海莱士血液制品股份有限公司 关于第六届监事会第七次会议决议的公告 本公司及监事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 上海莱士血液制品股份有限公司（"公司"）第六届监事会第七次会议于 2025 年 7 月 10 日以电子邮件和电话方式发出通知，并于 2025 年 7 月 15 日下午 3 点 以现场方式召开。 会议应出席监事 3 名，实际出席监事 3 名。本次会议由监事会主席张吉女士 召集和主持。会议的召集召开与表决程序符合《公司法》和《公司章程》的有关 规定。与会监事经过充分研究和讨论，审议并通过了如下议案： 1、《关于拟聘任 2025 年度会计师事务所的议案》 经审核，监事会认为：安永华明会计师事务所（特殊普通合伙）具备必要的 资质和独立性，具备相应的经验与能力，能够满足公司未来审计工作的需求，本 次聘任会计师事务所有充分和合理的理由。公司本次聘任会计师事务所的程序符 合相关法律、法规规定。公司监事会同意聘任安永华明会计师事务所（特殊普通 合伙）担任公司 2025 年度会计师事务所，并同 ...

Group 1 - The medical health ETF Taikang (159760) has seen a 0.17% increase, marking its fifth consecutive rise, while the index it tracks, the National Certificate Public Health and Medical Health Index (980016), rose by 0.13% [1] - As of July 14, the latest scale of the medical health ETF Taikang reached 82.4979 million yuan, a new high in nearly three months [2] - The medical device sector is expected to experience a performance turning point, driven by policies such as the old-for-new program and the gradual clearance of channel inventory [2] Group 2 - The top ten weighted stocks in the National Certificate Public Health and Medical Health Index account for 51.67% of the index, with leading companies including WuXi AppTec (603259) and Hengrui Medicine (600276) [3] - The CDMO sector has rebounded, with WuXi AppTec expected to see significant growth in revenue and profit by mid-2025, indicating strong global market demand [2] - The innovation drug industry chain is anticipated to enter a new upward cycle, supported by an improving domestic investment environment and active financing activities [2]

Core Insights - Human fibrinogen is recognized globally for its clinical application value in regulating coagulation function, with increasing demand driven by aging populations and rising living standards [1][13] - The market size for human fibrinogen in China is projected to grow from 1.529 billion yuan in 2021 to 2.15 billion yuan in 2024, reflecting a compound annual growth rate (CAGR) of 12.0% [1][13] - The production process of human fibrinogen is expected to improve with technological advancements, leading to enhanced product quality and continuous market growth [1][13] Industry Overview - Fibrinogen is a key substrate in the coagulation and hemostasis process, essential for maintaining normal coagulation and promoting platelet aggregation [3] - Human fibrinogen is derived from healthy human plasma, processed to remove viruses, and is used as an effective replacement therapy for fibrinogen deficiency [3] - The normal concentration of fibrinogen in the human body is maintained at 2-4 g/L, and it is crucial for correcting hypofibrinogenemia and improving coagulation disorders [3] Market Dynamics - The number of blood collection stations and plasmapheresis stations in China is increasing, with 3 new stations approved and 17 new operational stations in 2024, leading to a steady rise in plasma collection [8] - The total plasma collection volume in 2024 is expected to reach 13,400 tons, a year-on-year increase of 10.94%, with major companies like Tian Tan Biological, Taibang Biological, and Shanghai Raist accounting for approximately 80% of the domestic plasma collection [8] - The growth in the number of medical institutions, driven by an aging population and increased health awareness, is expected to boost the demand for human fibrinogen [11] Competitive Landscape - The human fibrinogen industry is attracting significant attention from capital markets, with increasing competition as more companies enter the field [17] - Key players in the industry include Huaren Boya Biological Pharmaceutical Group, Shanghai Raist Blood Products, and Beijing Tiantan Biological Products, among others [17][18] Future Trends - Continuous government policy support is expected to benefit the human fibrinogen market, with initiatives aimed at improving the quality and safety of blood products [22] - Companies are focusing on optimizing production processes and enhancing plasma utilization rates, which will drive overall industry progress [23] - The expansion of medical insurance coverage and rising consumer spending on healthcare are anticipated to gradually increase the market demand for human fibrinogen [24]

Group 1 - Morning Light Biological expects a net profit of 202.0 million to 232.0 million yuan for the first half of 2025, representing a year-on-year increase of 102.33% to 132.38% [1] - Northern Rare Earth anticipates a net profit of 900.0 million to 960.0 million yuan for the first half of 2025, with a significant year-on-year growth of 1882.54% to 2014.71% [1] - Youfa Group forecasts a net profit of 277.0 million to 307.0 million yuan for the first half of 2025, reflecting a year-on-year increase of 151.69% to 178.93% [1] Group 2 - Torch Electronics projects a net profit of approximately 247.0 million to 280.0 million yuan for the first half of 2025, indicating a year-on-year growth of 50.36% to 70.45% [3] - Zhiwei Intelligent expects a net profit of 91.98 million to 112.43 million yuan for the first half of 2025, with a year-on-year increase of 62.85% to 99.06% [4] - Youhao Group anticipates a net profit of 12.0 million yuan for the first half of 2025, representing a year-on-year growth of 51% [5] Group 3 - Nami Technology expects a net profit of 61.0 million to 73.0 million yuan for the first half of 2025, with a year-on-year increase of 35% to 62% [7] - Xinda Co. forecasts a net profit of 130.0 million to 150.0 million yuan for the first half of 2025, reflecting a substantial year-on-year growth of 2443.43% to 2834.73% [8] Group 4 - Shaanxi Coal Industry reported a coal production of 14.36 million tons in June, a year-on-year decrease of 5.07% [9] - Huanxu Electronics announced a consolidated revenue of 4.587 billion yuan in June, a year-on-year decline of 1.23% [10] Group 5 - Huadian International successfully issued 2.0 billion yuan in medium-term notes with a maturity of 3+N years and a coupon rate of 1.89% [20] - Zhongmin Energy reported a total power generation of 1.405 billion kilowatt-hours in the first half of 2025, a year-on-year decrease of 0.89% [20] Group 6 - Huaxia Biotech passed the FDA inspection with zero deficiencies, covering six major systems [21] - Ruikeda's application for convertible bond issuance has been accepted by the Shanghai Stock Exchange [22] Group 7 - Dafu Technology plans to invest no more than 100 million yuan in Anhui Yunta [42] - Tongda Co. won a bid for a project valued at 180.3 million yuan from the Southern Power Grid [46]

证券代码：002252 证券简称：上海莱士 公告编号：2025-050 上海莱士血液制品股份有限公司 关于"SR604 注射液"进入Ⅱb 期临床试验研究的公告 试验方案编号：LS-SR604-Ⅰ01 试验名称：评价 SR604 注射液在血友病 A/B 及先天性凝血因子Ⅶ缺乏症患 者中的安全性、耐受性、有效性、PK/PD 特征的开放、多中心Ⅰ/Ⅱ期临床试验 试验目的： Part A 剂量递增 Ⅰ 期试验（单次给药阶段）：评估 SR604 在血友病 A/B 患 者中单次给药后的安全性、耐受性和免疫原性、药代动力学特征。 Part B 疗效探索 Ⅱa 期试验/Part C 疗效探索Ⅱb 期试验（多次给药阶段）：评 估 SR604 在血友病 A/B 及先天性凝血因子Ⅶ缺乏症患者中多次给药的有效性、 药代动力学特征、安全性和其他有效性。 二、药物其他相关情况 SR604 注射液是一种人源化高亲和力结合人活化蛋白 C，特异性抑制人活化 蛋白 C 抗凝血功能的单克隆抗体制剂。按药品注册分类的治疗用生物制品 1 类 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 上海莱士血液 ...

证券代码：002252 证券简称：上海莱士 公告编号：2025-049 上海莱士血液制品股份有限公司 2024 年年度权益分派实施公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 特别提示： 1、根据《公司法》《深圳证券交易所上市公司自律监管指引第9号——回购 股份》等相关规定，公司通过回购专用证券账户持有的本公司股份50,973,052股 不享有参与本次权益分派的权利。公司2024年年度权益分派方案为：以分红派息 股权登记日总股本（扣除公司回购专用证券账户持有公司股票）为基数，向全体 股东每10股派发现金股利0.33元人民币（含税），本次利润分配公司不送红股， 不以公积金转增股本。 2、本次权益分派实施后，按公司总股本折算每10股现金分红比例及除权除 息参考价如下：考虑到公司回购专用证券账户上的股份不参与2024年年度权益分 派，公司本次实际现金分红的总金额=实际参与分配的总股本*分配比例= 6,587,011,785股*0.033元/股=217,371,388.91元；折算每10股现金红利=本次实际 现金分红的总金额÷总股本（含公司回购专用证券账户股份 ...

一、回购股份的进展情况 证券代码：002252 证券简称：上海莱士 公告编号：2025-048 上海莱士血液制品股份有限公司 关于回购公司股份的进展公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 上海莱士血液制品股份有限公司（"公司"）于 2025 年 1 月 13 日召开了第六 届董事会第七次（临时）会议，审议通过了《关于回购公司股份方案的议案》， 同意公司使用自有或自筹资金以集中竞价交易方式从二级市场回购公司股份，用 于实施员工持股计划或股权激励，拟回购股份的资金总额为不低于人民币 2.5 亿 元（含）且不超过人民币 5 亿元（含），拟回购股份价格不超过人民币 9.55 元/ 股（含），具体回购股份数量以回购股份方案实施完毕或回购实施期限届满时实 际回购情况为准。回购期限自股东大会审议通过本次回购股份方案之日起 12 个 月内，如果触及回购股份方案提及的相关条件时，回购期限提前届满。公司于 2025 年 2 月 14 日召开 2025 年第一次临时股东大会审议通过了上述股份回购方 案。具体内容详见公司分别于 2025 年 1 月 14 日、2025 ...

Core Viewpoint - The Chinese blood products industry is undergoing significant consolidation, with major players engaging in aggressive mergers and acquisitions to capture plasma resources, leading to the emergence of potential super giants in the sector [1][5]. Industry Landscape - The blood products industry in China is characterized by a "four-way" competitive landscape, dominated by four major groups: China National Pharmaceutical Group (Sinopharm), Haier Group, China Resources, and Hualan Biological Engineering [2][4]. - The industry has transitioned into a stock competition era since 2001, with new entrants needing to acquire existing licensed companies due to a moratorium on new licenses [2][3]. Mergers and Acquisitions - Significant acquisitions include China Resources' acquisition of Boya Biological for 4.8 billion yuan, Haier's 12.5 billion yuan acquisition of Shanghai Laishi, and Sinopharm's 4.5 billion yuan acquisition of Pilin Biological [1][2]. - The consolidation trend has led to a sharp increase in market concentration, with the top five companies' market share rising from under 50% in 2019 to over 70% by 2024 [4]. Plasma Collection and Utilization - Sinopharm's network includes 154 plasma collection stations, accounting for nearly 40% of the national total, with a collection volume of over 4,000 tons by mid-2025 [3]. - The cost structure of blood products heavily relies on raw plasma, which constitutes over 60% of total costs, making scale efficiency crucial for profitability [5][6]. Market Demand and Supply Gap - The domestic blood products market surpassed 60 billion yuan in 2023, with a demand gap of 4,000 tons, highlighting the need for leading companies to enhance their supply capabilities through technological upgrades [5][6]. - China's per capita consumption of blood products is significantly lower than that of developed countries, indicating a structural supply-demand imbalance [7][8]. Technological Advancements - Companies are shifting from a resource-driven model to a dual strategy of resource acquisition and research and development to overcome technological barriers and meet high-value product demands [9][10]. - Sinopharm and Hualan Biological are focusing on developing high-purity albumin and advanced coagulation factors, with significant investments in R&D to support these initiatives [10][11]. Future Outlook - The ongoing consolidation and technological advancements suggest that the Chinese blood products industry is on the verge of producing a super giant capable of competing globally [5][11]. - The combination of policy support, resource acquisition, and technological innovation is expected to drive the industry towards a more competitive and innovative future [10][11].