第44届摩根大通医疗健康年会持续至今日，期间涌现多项行业动态。英伟达与礼来宣布将在未来五年内 投入10亿美元，于旧金山湾区建设联合研究实验室，加速人工智能在制药行业的应用，双方工程师与医 学专家将协同构建AI模型推动新药研发。荣昌生物与艾伯维就新型靶向PD-1/VEGF双特异性抗体药物 RC148达成独家授权许可协议，艾伯维获得大中华区以外地区的相关开发、生产和商业化权利，荣昌生 物将获得首付款及相关里程碑付款与特许权使用费。约24家国内创新药企在会议上展示临床数据，主会 场演讲企业包含药明康德、药明生物等CXO公司以及百济神州等创新药企，另有17家企业参与亚太专 场。传奇生物在会上公布近期业务进展，其CARVYKTI累计治疗患者数已突破10000例，Raritan生产基 地扩建完成后成为美国规模最大的细胞疗法生产设施，公司预计2026年实现整体盈利。科伦博泰总裁兼 首席执行官葛均友博士在会上分享公司业务最新进展与创新战略。于保法教授携团队参会，展示肿瘤治 疗领域的缓释库疗法，引发广泛关注并初步建立国际合作意向。 药明康德：主营业务为覆盖药物研发生产全流程的CXO一体化服务，于年会上作为主会场演讲企业， 20 ...

中证500成长ETF华夏（159620）业绩比较基准为中证智选500成长创新策略指数收益率，管理人为华夏 基金管理有限公司，基金经理为荣膺，成立（2022-07-19）以来回报为26.34%，近一个月回报为 9.61%。 风险提示：市场有风险，投资需谨慎。本文为AI大模型自动发布，任何在本文出现的信息（包括但不 限于个股、评论、预测、图表、指标、理论、任何形式的表述等）均只作为参考，不构成个人投资建 议。 1月14日，截止午间收盘，中证500成长ETF华夏（159620）涨2.30%，报1.291元，成交额58.20万元。中 证500成长ETF华夏（159620）重仓股方面，长川科技截止午盘涨6.39%，科沃斯涨1.92%，百济神州涨 1.20%，广合科技涨1.90%，九号公司跌0.18%，晶晨股份涨3.40%，瑞芯微涨2.73%，恒玄科技涨 4.54%，三美股份涨0.37%，中瓷电子涨1.14%。 来源：新浪基金∞工作室 ...

Core Viewpoint - BeiGene's new drug, a BCL2 inhibitor named Baiyueda (sotoclisib), has officially launched in China, marking a significant advancement in treatment options for adult patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), as well as relapsed or refractory mantle cell lymphoma (MCL) [1] Group 1 - BeiGene's stock opened over 3% higher, reaching a price of 210.8 HKD with a trading volume of 16.78 million HKD [1] - The drug Baiyueda has commenced supply in 70 cities across China as of January 13 [1] - Multiple medical institutions nationwide have begun prescribing Baiyueda, allowing it to benefit patients with CLL/SLL and R/R MCL [1] Group 2 - Baiyueda received conditional approval from the National Medical Products Administration (NMPA) on December 30, 2025, based on positive results from clinical studies BGB-11417-201 and BGB-11417-202 [1] - The clinical results demonstrated significant remission benefits in treated CLL/SLL and R/R MCL patients, with good overall tolerability and safety [1]

Core Insights - The 44th JPMorgan Healthcare Conference (JPM 2026) took place from January 12 to 15 in San Francisco, focusing on biotechnology, biopharmaceuticals, and AI in medicine, serving as a significant investment and trading window for the global biopharmaceutical industry [2] Group 1: Market Reactions - Following the announcement of the JPM conference, both A-shares and Hong Kong stocks in the pharmaceutical sector saw a collective surge, with companies like Rongchang Biopharmaceutical, Hongbo Pharmaceutical, and Boji Pharmaceutical hitting the daily limit up in A-shares [2] - In Hong Kong, companies such as Cornerstone Pharmaceuticals, Qiming Medical, and Rongchang Biopharmaceutical also performed notably well [2] Group 2: Clinical Research and Innovations - A total of 24 domestic innovative pharmaceutical companies are set to showcase their clinical data at the JPM conference, with seven companies presenting in the main session, including WuXi AppTec and BeiGene [3] - BeiGene will discuss the progress of its core products, including the widely approved BTK inhibitor, Brukinsa, and its new BCL2 inhibitor, which is the first of its kind approved in China for treating certain lymphomas [3] - Ascentage Pharma will present advancements in its apoptosis pipeline, focusing on inhibitors targeting key proteins involved in cancer treatment [4] Group 3: Business Development and Collaborations - The JPM conference is expected to be a hotspot for business development (BD) transactions, with five BD deals already announced in January, showcasing China's leading position in various technological fields [6] - Rongchang Biopharmaceutical signed an exclusive licensing agreement with AbbVie for its new PD-1/VEGF dual-specific antibody drug, potentially worth up to $5.6 billion [6] - Yilian Biopharmaceutical reached a licensing agreement with Roche for its YL201 project, securing an upfront payment of $570 million and additional milestone payments [6] Group 4: AI in Pharmaceuticals - The rapid development of AI has made it a focal point for many innovative pharmaceutical companies, with firms like Hengrui Medicine and BeiGene integrating AI technologies into their drug development processes [5] - NVIDIA and Eli Lilly announced a $1 billion investment to establish a joint research lab in the San Francisco Bay Area to accelerate AI applications in the pharmaceutical industry [5]

BeOne Medicines (NasdaqGS:BGNE) FY Conference January 13, 2026 10:30 AM ET Company ParticipantsJohn Oyler - Co-founder, Chair and CEOConference Call ParticipantsJess Fye - Biotech AnalystJess FyeGreat. Good morning, everyone. My name's Jess Fye. I'm a large-cap Biotech Analyst at JPMorgan. And we're continuing the 44th Annual Healthcare Conference today with BeOne. First, you're going to hear a presentation from the company, and then we're going to go into a little Q&A. If you are in the room, you know, rai ...

T H E F U T U R E I S N O W BeOne Medicines 44th Annual J.P. Morgan Healthcare Conference 2026 JANUARY 13, 2026 Over 25 years, cancer outcomes have dramatically improved, but there is still work to be done 5-year survival rate in U.S. (%)1 Leukemia Myeloma Ovarian Stomach Lung Liver Pancreatic 0% 50% 100% 51 68 15 28 35 62 24 36 44 52 11 22 5 13 1999 - 2001 2015 - 2021 Patients diagnosed: 1 SEER data published April 2025 Leukemia includes ALL, AML, CLL, CML 2 Gene therapy Immuno-oncology Degraders Bispecifi ...

创新药专题推荐电话会议——以 De-Risking 路径锁定创 新药高成长机会 20260112 摘要 2025 年创新药板块受益于 BD 交易额超预期，全年交易额超 1,000 亿 美元，中国创新药公司收入规模预期增加约 6 倍，行业进入爆发期。 中国已成为全球 PCC 到 POC 效率最高的国家之一，拥有优质临床资源 和高效开发能力，未来将涌现更多 Best/First in class 创新药，带来投 资机会。 百济神州泽布替尼预计 2025 年全球销售额达 37 亿美元，2027 年或增 至 45-50 亿美元，为其他企业树立标杆，头部企业引领贝塔机会。 推荐关注百济神州、科伦博泰（与默沙东合作）、信达生物（与武田合 作）及康方翰森等创新药公司，以及亿方生物、信立泰等高弹性投资机 会。 2026 年摩根大会、ACR、ASCO、ESMO 等学术会议将披露重要临床 数据，影响相关公司股价，上半年关注 ACR-ASCO，下半年关注肺癌大 会及 ESMO。 Q&A 2026 年创新药投资的主要逻辑是什么？ 2026 年创新药投资的主要逻辑是 de-risking。经过 2025 年的系统性资产价 值重估后，更 ...

Investment Rating - The report indicates a positive investment outlook for the pharmaceutical sector, with the overall performance of the Shenwan Pharmaceutical and Biological Index increasing by 7.8% during the week, outperforming the Shanghai Composite Index which rose by 3.82% [2][3]. Core Insights - The pharmaceutical sector's overall valuation stands at 30.6 times earnings, ranking 10th among 31 Shenwan primary industries [5]. - The report highlights significant developments in the long-term care insurance system transitioning from pilot programs to full establishment during the 14th Five-Year Plan, with coverage reaching nearly 300 million people and fund expenditures exceeding 100 billion yuan by the end of 2025 [11]. - Notable advancements in drug commercialization include the launch of Novo Nordisk's oral GLP-1 weight loss drug Wegovy in the U.S., with monthly costs ranging from $149 to $299 for self-paying patients [13][14]. - Moderna has submitted a New Drug Application (NDA) for its seasonal flu vaccine mRNA-1010, showing promising efficacy results in clinical trials [15]. - Arrowhead has reported positive mid-stage results for its RNAi therapies ARO-INHBE and ARO-ALK7, demonstrating significant reductions in visceral and liver fat [16][17]. - GSK's hepatitis B drug Bepirovirsen has shown statistically significant functional cure rates in its Phase III trials [18]. - Recent approvals for innovative drugs in China include BeiGene's BCL-2 inhibitor and Sanofi's APOC3 siRNA drug, which addresses familial chylomicronemia syndrome [19][21]. Summary by Sections Market Performance - The Shenwan Pharmaceutical and Biological Index increased by 7.8%, ranking 6th among 31 Shenwan primary industries [2][3]. - Various sub-sectors showed positive growth, with medical devices and medical outsourcing leading with increases of 10.8% and 11.1%, respectively [5]. Industry Dynamics - The long-term care insurance system is set to expand significantly, with a focus on providing care for the elderly and disabled [11][12]. - The report emphasizes the importance of innovation in drug development, particularly in RNAi therapies and small nucleic acid drugs, which are gaining traction in clinical settings [16][18]. Company Developments - Significant partnerships and collaborations are highlighted, such as the $8.88 billion research collaboration between Insilico Medicine and Servier focusing on oncology [20]. - The report notes the successful commercialization of several new drugs, including BeiGene's and Sanofi's recent approvals, which are expected to impact market dynamics positively [19][21]. - The establishment of new companies and subsidiaries, such as the brain-computer interface subsidiary by Xinwei Medical, indicates a strategic shift towards innovative technologies in healthcare [22].

Investment Rating - The report maintains a positive outlook on the pharmaceutical industry, indicating a "Buy" rating based on recent market performance and emerging opportunities in innovative drug development [2][3]. Core Insights - The pharmaceutical sector saw a significant increase, with the Shenwan Pharmaceutical and Biological Index rising by 7.8%, outperforming the Shanghai Composite Index, which increased by 3.82% [2][3]. - The report highlights the ongoing commercialization of innovative drugs, including the oral GLP-1 medication Wegovy by Novo Nordisk, and the successful clinical trials of various RNAi therapies [11][13][18]. - The establishment of a comprehensive long-term care insurance system in China is expected to enhance the healthcare landscape, potentially benefiting the pharmaceutical sector [11][12]. Market Performance - The Shenwan Pharmaceutical and Biological Index ranked 6th among 31 Shenwan first-level sub-industries, with various sub-sectors showing positive growth, such as medical devices (+10.8%) and medical research outsourcing (+11.1%) [2][5]. - The overall valuation of the pharmaceutical sector stands at 30.6 times earnings, ranking 10th among 31 Shenwan first-level industries [5][10]. Recent Key Events - The report notes the successful approval and commercialization of several new drugs, including BeiGene's BCL-2 inhibitor and Sanofi's APOC3 siRNA drug, which address significant medical needs [20][22]. - Collaborations in drug development are highlighted, such as the $8.88 billion partnership between Insilico Medicine and Servier focusing on oncology [21]. - The report emphasizes the potential of the brain-computer interface industry, with companies like Mindray Medical and Lepu Medical making strides in this area [24]. Investment Opportunities - The report suggests focusing on domestic innovative drug companies and CROs, particularly those involved in the development of small nucleic acid drugs and brain-computer interface technologies [2][11]. - Specific companies to watch include Tigermed, WuXi AppTec, and Innovent Biologics, which are positioned to benefit from the recovery of the innovative drug sector [2][11].

Group 1 - The A-share and Hong Kong stock markets showed strength on January 12, with the innovative drug concept experiencing fluctuations after several days of rebound; the Hang Seng-Hushen-Hong Kong Innovative Drug Selected 50 Index fell by 0.63% at the time of reporting, while stocks like CSPC Pharmaceutical Group, BeiGene, and Boteng Co., Ltd. saw slight increases [1] - Since the beginning of 2026, as of the close on January 9, the Hang Seng-Hushen-Hong Kong Innovative Drug Selected 50 Index has rebounded over 10% cumulatively [1] - The Tianhong Innovative Drug ETF (517380) was actively traded, with a transaction amount exceeding 40 million yuan and a premium rate of 0.78% at the time of reporting; it has seen continuous capital inflow, accumulating over 170 million yuan from January 7 to 9 [1] Group 2 - According to Zhongtai Securities, it is recommended to focus on three dimensions for investment in 2026: "innovative drugs and their industrial chain, demand recovery and operational turning points, and AI+" [2] - Continuous attention should be paid to the AI+ theme, the positive catalysts from the JPM conference in the innovative drug sector, and the potential for exceeding annual performance forecasts or clearing turning point opportunities [2]