④【谷歌母公司Alphabet拟发行百年债券】2月10日，据媒体援引知情人士透露，谷歌母公司Alphabet已启动其首次瑞士法郎债券发行。此次发行包含3 年、6年、10年、15年和25年期债券，预计将在今日晚些时候定价。同时，谷歌母公司Alphabet也启动首次英镑债券发行。此次交易分为3年、6年、15 年、32年和100年期债券，预计将在今日晚些时候定价。 ⑤【1月销售额同比飙升36.8％，台积电涨超3%】当地时间2月10日，台积电官网显示，1月销售额达到4012.6亿元台币，同比增长36.8％，较2025年12月 环比增长19.8%，超过台积电预期的全年30%增长水平。截至发稿，台积电上涨3.09%。 ⑥【暂停股票回购，英国石油公司跌近5%】2月10日，英国石油公司Q4财报显示，基准重置成本利润（作为净利润的替代指标）为15.4亿美元，与分析师 预期15.4亿美元一致。英国石油公司2025年全年净利润为74.9亿美元，低于分析师预期的75.8亿美元，较2024年的近90亿美元有所下滑。英国石油公司同 时表示，决定暂停股票回购，旨在通过调整财务状况来应对油价下跌带来的影响。截至发稿，英国石油公司下跌4.9% ...

高盛相信，信达生物将继续保持其在中国生物技术领域的领先地位，主要得益于拥有大量针对下一代免疫 肿瘤靶点的新型分子，并已获得令人鼓舞的初步数据(如IBI363(PD-1/IL-2α偏向性双特异性抗体)，在免疫治 疗/冷肿瘤中具有差异化的药物特性；强大的商业化能力及与全球合作伙伴，特别是礼来公司的深度合作等。 信达生物(01801):与礼来(LLY.US)深化长期合作关系料被低估,予"买入"评级 高盛发布研报称，信达生物(85.25,5.75,7.23%)(01801)昨日(8日)宣布与礼来(LLY.US)美元的里程碑付 款；及基于中国以外地区净销售额的分级销售特许权使用费。高盛考虑到当前市场隐含的加权平均资本成本 (12%)较高，认为其目前股价被低估；予该股"买入"评级；基于风险调整后、现金流量折现法，予目标价 102.85港元。 美国高盛 ...

在电话会议上，信达生物管理层重申其长期愿景，主要受惠于通用生物药和肿瘤药领域双引擎增长策略 的支持。该行对信达生物在其商业及研发产品线上的执行力，以及其强大的业务拓展能力持续印象深 刻。 该行认为此次合作属正面惊喜，标志着信达生物迈向全球性生物制药公司历程中的又一个重要里程碑， 并突显其研发平台的实力。 智通财经APP获悉，摩根大通发布研报称，信达生物(01801)与礼来(LLY.US)达成战略合作，共同在全球 范围开发聚焦于肿瘤和免疫学领域的新型生物制剂。小摩重申信达生物是其所覆盖的中国生物科技公司 中的首选标的之一，予其"增持"评级，目标价为111港元。 ...

格隆汇2月10日｜德意志银行将礼来的目标价从1200美元上调至1285美元，维持"买入"评级。(格隆汇) ...

The stock has climbed in the triple digits over the past three years.Eli Lilly (LLY 1.28%) has already scored major accomplishments in the GLP-1 boom. The company has delivered double-digit revenue growth, taken leadership in the market, and seen its stock price explode higher. GLP-1 drugs have been in great demand as they've helped people quickly and safely shed pounds.Now, though, after Lilly stock's 200% increase over three years, you may be wondering if the growth story has fully played out or if there' ...

Investment Rating - The investment rating for the industry is "Positive" and the rating has been maintained [1] Core Insights - The pharmaceutical and biotechnology industry index experienced a decline of 3.17%, ranking 22nd among 31 primary industries, underperforming the CSI 300 index which fell by 1.25% [6][17] - The valuation of the pharmaceutical and biotechnology industry as of February 6, 2026, is a PE (TTM overall method, excluding negative values) of 29.57x, down from 30.31x in the previous period, indicating a downward trend below the average [6][22] - The top three sub-industries in terms of PE (TTM overall method, excluding negative values) are vaccines (46.30x), hospitals (43.34x), and medical consumables (37.71x), while the median is 32.64x, with pharmaceutical distribution having the lowest valuation at 14.88x [22] Industry Trends - The focus in the global pharmaceutical market is on GLP-1 targets, with Eli Lilly's Tirzepatide establishing a leading position in the metabolic disease field due to its clinical value and commercialization performance [9] - The collaboration model between multinational pharmaceutical companies and Chinese biopharmaceutical firms is evolving towards "platform capabilities + multi-project combinations," highlighting the long-term strategic value of underlying innovative capabilities such as sustained delivery technology and peptide R&D platforms [9] - The investment logic in the industry is shifting from single blockbuster products to platform-based, matrixed approaches, and key supply chain segments [9] Investment Recommendations - Focus on innovative pharmaceutical companies with "core technology platforms + diversified pipelines," as their ability to derive multiple values from platforms and achieve cross-border collaboration milestones will be a key advantage [9] - Pay attention to industry chain segments benefiting from drug long-acting and oral trends, including complex formulation processes, high-end delivery technologies, and related peptide CDMO fields [9] - In the context of strong global R&D and production demand, peptide CXO companies that are active in cross-border collaborations, have balanced customer structures, and possess solid compliance systems will continue to share in the industry's high prosperity dividends [9]

科创创新药ETF汇添富（589120）标的指数成分股多数冲高，荣昌生物、百利天恒涨超5%，百济神州涨超4%，泽璟制药、博瑞医药等涨幅居前， 特宝生物、益方生物等小幅回调。 【科创创新药ETF汇添富（589120）标的指数前十大成分股】 | 序号 | 代码 | 名称 | 申万一级行业 | 涨跌幅 | 估算权重 | | --- | --- | --- | --- | --- | --- | | 1 | 688235 | J-Z**KD | 医药生物 | 4.04% | 10.43% | | 2 | 688578 | 艾力斯 | 医药生物 | 0.82% | 9.10% | | 3 | 688506 | 百利天恒 | 医药生物 | 5.10% | 7.89% | | র্ব | 688180 | 君实生物-U | 医药生物 | 1.10% | 6.70% | | 5 | 688331 | 荣昌生物 | 医药生物 | 5.51% | 6.35% | | 6 | 688266 | 泽昌制药-U | 医药生物 | 3.74% | 6.07% | | 7 | 688166 | 博瑞医药 | 医药生物 | 2.27% | 4 ...

截至2026年2月10日 10:49，恒生港股通创新药指数(HSSCID)强势上涨4.32%，港股通创新药ETF易方达 (159316)上涨3.50%， 冲击3连涨。盘中换手9.42%，成交4.03亿元。 港股通创新药ETF易方达(159316)紧密跟踪恒生港股通创新药指数，恒生港股通创新药指数旨在反映可 经港股通买卖，业务与创新药研究、开发及生产相关的香港上市公司之表现。 相关产品 根据合作协议，信达生物依托自身成熟的抗体技术平台及高效的临床能力，将主导相关项目从药物发现 至中国临床概念验证（二期临床试验完成）的研发工作。根据协议，礼来获得相关项目在大中华区以外 的全球独家开发与商业化许可，信达生物保留相关项目在大中华区的全部权利。根据协议条款，信达生 物将获得 3.5 亿美元首付款；在达成后续特定里程碑事件后，信达生物还有资格获得总额最高约85亿美 元的研发、监管及商业化里程碑付款。此外，信达生物有权就各产品在大中华区以外的净销售额获得梯 度的销售分成。 中邮证券认为，创新药板块虽短期受资金面扰动有所回调，但产业层面全球参与度提升趋势已在2025年 充分体现；国产新药正从早研追赶迈向效率制胜阶段，中期维度 ...

瑞银发表研报指，信达生物与礼来就多项早期肿瘤及免疫学资产达成合作。协议包括3.5亿美元的首付 款，潜在里程碑付款最高达85亿美元，以及基于净销售额的分层权利金。该行对两间公司进行第7次合 作持积极看法，并认为相较于以往的对外授权，是次成立新公司及共同开发模式，是一种新的合作模 式。信达生物指出，是次合作的潜在资产数量较同业其他类近的合作少，且财务条款优厚。更重要是， 该行注意到潜在资产包括信达生物研发管线中未出现过的新资产，为公司原先指引每年推进8至10个候 选药物进入临床阶段的目标带来上行空间。该行现予公司目标价137.4港元及"买入"评级。 ...

Investment Rating - The report does not explicitly state an investment rating for the industry Core Insights - The proportion of driver gene-negative non-small cell lung cancer (NSCLC) patients is approximately 31% in both China and the United States, indicating a significant market opportunity for treatments targeting this demographic [2][15] - The estimated market size for immune drugs used in first-line treatment of driver gene-negative NSCLC is projected to be around 7.5 billion CNY (approximately 1.1 billion USD) in China and 18 billion CNY (approximately 2.7 billion USD) in the United States by 2030 [2] - The current first-line treatment for advanced driver gene-negative NSCLC primarily relies on PD(L)-1 inhibitors combined with chemotherapy, but there are limitations in long-term efficacy and options for patients intolerant to chemotherapy [3] Summary by Sections Section 1: NSCLC Global Overview - Lung cancer is the leading cancer type globally, with new cases accounting for approximately 12% of all cancer cases in 2022, translating to about 2.5 million new lung cancer cases [10] - In China, lung cancer represents about 22% of new cancer cases, with approximately 1.06 million new cases in 2022 [10] Section 2: Market Potential for Driver Gene-Negative NSCLC - The report highlights the significant market potential for immune therapies in treating driver gene-negative NSCLC, with a focus on the limitations of current treatment options [2][3] Section 3: Next-Generation Immunotherapy Approaches - The report discusses the advancements in dual (multi) antibody therapies and immune-oncology (IO) combined with antibody-drug conjugates (ADC), emphasizing their potential to improve treatment outcomes for patients with driver gene-negative NSCLC [5][8] - The clinical data supporting these new therapies is expected to catalyze further investment and development in this area [5] Section 4: Treatment Guidelines Comparison - The report compares treatment guidelines for driver gene-negative NSCLC between the United States and China, noting differences in treatment stratification and recommended therapies [32][34] - The U.S. guidelines emphasize PD-L1 expression levels, while Chinese guidelines focus more on performance status (PS) [32][34] Section 5: Future Catalysts - Key upcoming clinical data releases and studies are highlighted as potential catalysts for investment opportunities in the sector, particularly regarding dual antibodies and ADC therapies [5][8]