Financial Performance & Outlook - Revenue for Q1 2025 was $40.8 million[10] - The company is targeting revenue in the range of $165 million to $175 million for 2025[10] - Non-GAAP operating expenses decreased by 22% year-over-year in Q1 2025[10, 17, 53] - Adjusted EBITDA improved by 29% year-over-year in Q1 2025[10, 17, 58] - Non-GAAP Gross Margin was 53% in Q1 2025[49] Cash Position & Cost Reduction - The company had $261 million in cash, cash equivalents, restricted cash, and short-term investments as of March 31, 2025[10, 22, 62] - The company operationalized approximately $10 million in cost reductions in Q1 2025, totaling $90 million since the merger[10] Strategic Initiatives - The company is rolling out new proteomics solutions and Illumina NGS[10] - The company is targeting adjusted EBITDA positive in 2026[10, 19, 64] SomaLogic Merger - The company is targeting $80 million in synergies from the SomaLogic merger[19, 22]

Core Viewpoint - Nautilus Biotechnology, Inc. reported financial results for Q1 2025, highlighting progress in its Tau proteoform assay and a reduction in operating expenses, while also noting a net loss that improved compared to the previous year [1][2][4]. Financial Performance - Operating expenses for Q1 2025 were $18.8 million, a 13% decrease from $21.6 million in Q1 2024, attributed to cost optimization and reduced stock-based compensation [3]. - The net loss for Q1 2025 was $16.6 million, compared to a net loss of $18.7 million in the same period last year [4][12]. - Cash, cash equivalents, and investments totaled $192.8 million as of March 31, 2025 [4]. Business Development - The CEO emphasized the assay's reproducibility, accuracy, and compatibility with customer needs, indicating confidence in the platform's application in Alzheimer's and neurodegenerative disease research in 2025 [2]. - The company is focused on advancing its proteome analysis platform, aiming to democratize access to proteomics and enhance research capabilities in human health [6]. Cash Flow and Investments - Cash flows from operating activities showed a net cash used of $13.9 million for Q1 2025, an improvement from $16.3 million in Q1 2024 [13]. - The company generated $19.5 million from investing activities, primarily from securities maturities [14]. Balance Sheet Overview - Total assets as of March 31, 2025, were $227.7 million, down from $242.7 million at the end of 2024 [10][11]. - Total liabilities were $33.3 million, slightly decreased from $34.0 million at the end of the previous year [11]. - Stockholders' equity was $194.4 million, down from $208.7 million at the end of 2024, with an accumulated deficit of $289.6 million [11].

Expanded suite of consumables, instruments and services designed to empower researchers and accelerate next- generation drug development Ninety posters and presentations at AACR powered by the Standard BioTools proteomic portfolio to advance cancer research from target discovery to clinical development SOUTH SAN FRANCISCO, Calif., April 24, 2025 (GLOBE NEWSWIRE) -- Standard BioTools Inc. (NASDAQ:LAB) today announced the launch of new and enhanced proteomic product offerings at the upcoming American Associat ...

Financial Data and Key Metrics Changes - Total revenue for 2024 was $71.3 million, representing a 45% year-over-year growth [6][23] - Gross margins increased to 78% for the year, up from 73% in 2023 [7][25] - Adjusted EBITDA loss improved by 32% year-over-year, indicating progress towards profitability [7][28] - Net loss for Q4 2024 was $8.3 million, a 10% improvement compared to Q4 2023 [28] Business Line Data and Key Metrics Changes - Lung diagnostic testing revenue for Q4 2024 was $17.2 million, a 34% increase in revenue and test volume compared to Q4 2023 [24] - Full-year lung diagnostic testing revenues reached $64.7 million, reflecting a 43% growth [24] - Diagnostic development services revenue grew by 72% in Q4 and 70% for the full year [24] Market Data and Key Metrics Changes - The company reported a 40% growth in test volume for lung diagnostic testing in 2024 [9][24] - Approximately 49% of lung nodule patients have their first imaging workup conducted by primary care providers, indicating a significant market opportunity [11] Company Strategy and Development Direction - The company aims to expand its sales force by adding approximately six sales teammates per quarter in 2025, increasing from 71 to 95 teammates [13][31] - A new clinical study, Clarify, was launched to collect patient outcomes and clinical information, expected to provide valuable data in 2025 [14][17] - The company plans to maintain strong gross margins in the mid to upper seventies while achieving adjusted EBITDA profitability in the second half of 2025 [22][25] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in transforming patient care through personalized diagnostics, particularly in lung disease [7][31] - The company anticipates significant growth in 2025 driven by lung diagnostic testing and diagnostic development services [22][32] - Management highlighted the importance of addressing the unmet medical need in lung disease, with a focus on early diagnosis and treatment [8][31] Other Important Information - The company ended Q4 2024 with $26.2 million in unrestricted cash and cash equivalents [29] - A pilot program in 2024 demonstrated the effectiveness of expanding referral networks to primary care providers [12][41] Q&A Session Summary Question: Can you provide insights on revenue guidance between test business and biopharma business? - Management expects biopharma services to contribute about 8-9% of total revenue, with the majority coming from lung diagnostic services [39] Question: What are the drivers for adjusted EBITDA profitability? - Revenue growth combined with tight control on expenses will help achieve adjusted EBITDA breakeven in the second half of 2025 [40] Question: Can you elaborate on the pilot program's findings? - The pilot showed that primary care physicians were accessible and recognized the utility of the tests, leading to better patient management [42][45] Question: What is the status of the product pipeline? - No new tests will be launched in 2025, but updates on existing partnerships and studies will be provided throughout the year [54] Question: How will updates in lung cancer screening guidelines affect the company? - Management believes that any improvements in screening will significantly expand the addressable market for their services [62][66] Question: What is the expected cash burn for the year? - Management anticipates cash burn to increase in Q1 but expects to reach cash flow breakeven with existing cash on hand [106][110]

As filed with the Securities and Exchange Commission on June 13, 2024 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 IMAC HOLDINGS, INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) Delaware 8093 83-0784691 (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identification No.) 3401 Mallory Lane, Suite 100 ...