Market Overview - On May 23, A-shares experienced a collective pullback, with the Shanghai Composite Index down 0.94% closing at 3348.37 points, the Shenzhen Component down 0.85% at 10132.41 points, and the ChiNext Index down 1.18% at 2021.50 points [1] - The trading volume in the Shanghai and Shenzhen markets reached 115.56 billion, an increase of 52.9 billion compared to the previous day [1] - The market saw more stocks decline than rise, with over 1100 stocks increasing and more than 50 hitting the daily limit up [1] Sector Performance - Precious metals, chemical pharmaceuticals, and medical services sectors showed the highest gains, while shipping ports, gaming, trade, internet services, and diversified finance sectors faced the largest declines [1] - The market's cautious sentiment was reflected in the trading patterns, with significant fluctuations observed in micro-cap stocks and the North Exchange [3][5] Notable Stocks - Wangzi New Materials saw a significant price increase of nearly 60% since May 15, driven by developments in controllable nuclear fusion projects [7] - The stock experienced high volatility, with daily trading ranges exceeding 20% on May 21 and 16.01% on May 23, indicating strong market speculation and liquidity risks [7] - Heng Rui Pharmaceutical's H-shares debuted on the Hong Kong Stock Exchange, surging approximately 37% at one point, with a market capitalization exceeding 380 billion HKD [9][11] Investment Sentiment - Analysts remain cautiously optimistic about the market's future, suggesting a continuation of index fluctuations and sector rotations [9] - The pharmaceutical sector is expected to regain stability and growth, supported by ongoing innovations and favorable policies [12] - The biotechnology ETF saw an increase of over 1%, reflecting positive sentiment in the biopharmaceutical industry [12]

恒瑞医药：公司H股股票于2025年5月23日挂牌并上市交易 智通财经5月23日电，恒瑞医药(600276.SH)公告称，公司本次全球发售H股总数为2.25亿股（行使超额 配售权之前），每股H股发售价44.05港元，扣除相关费用后，并假设超额配售权未获行使，公司将收取 的全球发售所得款项净额约为97.47亿港元。公司H股股票于2025年5月23日在香港联交所主板挂牌并上 市交易，中文简称为"恒瑞醫藥"，英文简称为"HENGRUIPHARMA"，股份代号为"1276"。 ...

Core Viewpoint - The Hong Kong stock market experienced fluctuations, with the Hang Seng Index closing up by 0.24% at 23,601.26 points, driven by the strong performance of newly listed stocks, particularly 恒瑞医药 (Hengrui Medicine) which surged over 25% on its debut [1] Market Performance - The Hang Seng Index recorded a trading volume of 203.67 billion HKD [1] - The Hang Seng Technology Index declined by 0.09%, closing at 5,246.87 points [1] Sector Performance - The innovative drug sector saw significant gains due to the listing of 恒瑞医药, contributing to a broader rally in the market [1] - The automotive parts and film sectors also showed strong performance, while the clothing retail sector faced declines [1] Individual Stock Highlights - Mirxes-B (02629.HK) rose by 28.76% on its first trading day [1] - 恒瑞医药 (01276.HK) increased by 25.2% [1] - BYD Company (01211.HK) saw an increase of nearly 2% [1] - Alibaba Pictures (01060.HK) rose by 8% [1] - China Health Group (00673.HK) resumed trading and surged over 110% [1] - Tmall (06110.HK) fell by over 9.4% [1] - Chow Tai Fook (01929.HK) decreased by 3.3% [1] - Xpeng Motors (09868.HK) dropped by 3.9% [1]

【恒生指数收涨0.24%，恒瑞医药上市首日大涨】恒生科技指数收跌0.09%，盘中一度涨超1%；医药股 走高，恒瑞医药上市首日收涨逾25%，石药集团涨超2%；比亚迪股份涨近2%，公司在欧洲的电动汽车 销量首次超越特斯拉。 ...

消息面上，在创新治疗领域，中国企业的国际合作一直在持续。此前，百利天恒将双抗AD授权给百时 美施贵宝，以84亿美元的金额刷新了中国ADC新药"出海"的交易金额纪录。而刚实现"A+H"两地上市的 恒瑞医药近年来的BD更是进展迅速。截至目前，恒瑞医药已经实现14笔创新药License-out（对外授 权），其中近三年对外授权9笔，合作方包括默克、默沙东等国际巨头，涉及GLP-1、ADC等热门领 域。2024年中国创新药对License-out完成94笔，出海交易总金额高达519亿美元，同比增长26%。 大而全：创新药ETF（159992）跟踪创新药指数，该指数布局创新药产业链龙头企业，既汇聚全球CXO 龙头企业，又包含国内仿创药企龙头，有望同时受益于AI赋能创新药、国产创新药出海、针对高价创 新药的医保丙类目录出台等。 中信建投证券认为，创新药板块近年来展现出强劲的技术驱动发展势头，尤其在抗体偶联药物 （ADC）、双特异性抗体（双抗）以及小分子疗法等领域取得了显著进展。以2025年美国临床肿瘤学 会（ASCO）年会为例，中国创新药企在此次会议上提交了超过70项口头报告，其中Late Breaking Abstra ...

Core Viewpoint - The pharmaceutical sector in China is experiencing significant growth, driven by favorable government policies and increasing international market share, with a notable rise in innovative drug development and exports [1][2]. Group 1: Market Performance - On May 23, 2025, pharmaceutical stocks collectively surged, with sectors like Helicobacter pylori, AI healthcare concepts, and weight-loss drugs rising over 2% [1]. - Hai Chen Pharmaceutical's stock hit a 20% limit up within three minutes of opening, reaching a new high in two and a half years [1]. - Heng Rui Pharmaceutical officially listed on the Hong Kong stock market, with its stock price increasing by approximately 30% post-opening, raising about 9.9 billion HKD through an IPO of 224.5 million shares, marking the largest IPO in the Hong Kong pharmaceutical sector in five years [1]. Group 2: Export and Innovation - In Q1 2025, China's pharmaceutical and healthcare product exports reached 26.632 billion USD, a year-on-year increase of 4.39%, while imports decreased by 4.42% to 20.456 billion USD, indicating a domestic industry upgrade and import substitution effect [1][2]. - The United States remains the largest single market for Chinese pharmaceutical exports, with exports amounting to 4.639 billion USD, a 9.6% increase, primarily driven by raw materials and disposable medical supplies [2]. - By the end of 2024, the number of active innovative drugs developed by Chinese companies reached 3,575, ranking first globally, with domestic products accounting for 42% of newly approved innovative drugs, up from less than 10% in 2015 [2]. Group 3: Future Outlook - Analysts predict that 2025 will be a pivotal year for the pharmaceutical industry in China, marking the beginning of significant revenue growth, profitability for many companies, and an extended valuation cycle due to improvements in payment systems [2].

Market Overview - A-shares experienced slight fluctuations with major indices showing minor gains, including the Shanghai Composite Index rising for the fourth consecutive day [1] - The trading volume continues to shrink, indicating a potential decrease in market activity [1] Key Indices Performance - Shanghai Composite Index: 3,382.96 (+0.08%) - Shenzhen Component Index: 10,271.21 (+0.50%) - ChiNext Index: 2,055.44 (+0.48%) - Shanghai 50 Index: 2,738.01 (+0.16%) - CSI 300 Index: 3,925.58 (+0.30%) - STAR 50 Index: 993.56 (+0.29%) - North Exchange 50 Index: 1,410.71 (+1.58%) - CSI 1000 Index: 6,079.58 (+0.22%) [2] Pharmaceutical Sector - The pharmaceutical sector showed strong performance with significant gains in various sub-sectors, including AI healthcare and weight loss drugs, with some stocks reaching their daily limit [3] - Hengrui Medicine's H-shares debuted on the Hong Kong Stock Exchange, surging over 37% during trading, raising approximately HKD 9.9 billion, marking the largest IPO in the Hong Kong pharmaceutical sector in five years [5] Innovation in Pharmaceuticals - China's pharmaceutical industry is rapidly developing, with exports reaching USD 26.632 billion in Q1 2025, a 4.39% increase year-on-year, while imports decreased by 4.42% to USD 20.456 billion [7] - The number of active innovative drugs developed by Chinese companies reached 3,575 by the end of 2024, ranking first globally, with domestic products accounting for 42% of approved innovative drugs [7] Automotive Industry - The automotive supply chain was active, with various segments such as passenger cars and automotive components showing strong gains [8] - The passenger car market saw sales of 6.872 million units from January to April, a 7.9% increase year-on-year, while the new energy vehicle market experienced a 35.7% increase with sales of 3.324 million units [10] Solid-State Battery Developments - The solid-state battery sector received positive news, with the China Automotive Engineering Society releasing standards for solid-state batteries, facilitating technological upgrades [11] - Companies like Funeng Technology and Guoxuan High-Tech are making significant advancements in solid-state battery development, with plans for commercial delivery of products by the end of 2025 [11]

每经记者｜甄素静 每经编辑｜陈俊杰 5月23日，"药王"恒瑞医药在港交所正式挂牌上市，成功实现"A+H"两地上市。此次恒瑞医药全球发售约2.3亿股，发行定价为44.05港元/股，该发行价格为 预计发行价格的上限。 恒瑞医药H股首日上市交易，开盘上涨29.40%，开盘价为57.00港元/股。截至上午收盘，上涨30.65%。 恒瑞医药港股上市现场 每经记者 甄素净 摄 《每日经济新闻》记者在恒瑞医药港股上市现场看到，恒瑞医药管理层齐聚一堂，公司董事长孙飘扬参加了上市敲锣环节，公司执行董事兼副董事长戴洪斌 致辞。香港交易所上市委员会副主席黄嘉信在开场介绍了恒瑞医药及其在港股上市的基本情况。 戴洪斌在上市致辞环节表示，此次港股上市标志着恒瑞医药在登陆上海证券交易所25年后，正式完成"A+H"双资本平台布局。戴洪斌特别感谢了股东、合作 伙伴和客户的信任，以及香港交易所、证监会等在公司上市过程中提供的帮助。他指出，今年正值恒瑞医药成立 55 周年，经过多年发展，公司已逐步成长 为一家创新国际化的大型制药上市企业，连续六年跻身美国《制药经理人》杂志全球制药企业TOP50榜单。 戴洪斌还表示，登陆港股是恒瑞医药迈向国际资本市 ...

Core Viewpoint - The pharmaceutical sector in Hong Kong and A-shares has experienced a significant surge, driven by the upcoming 2025 American Society of Clinical Oncology (ASCO) annual meeting where multiple innovative drug companies will showcase their research results. The market is optimistic about the potential of Chinese innovative drugs entering the global market, particularly following the collaboration between 3SBio and Pfizer on a PD-1/VEGF dual antibody [1][3][6]. Group 1: Market Performance - The Hong Kong pharmaceutical sector saw a broad rally, with the Hang Seng Healthcare Index rising over 2%. Notable stock performances included a more than 15% increase for Haijia Medical and over 11% for Green Leaf Pharmaceutical [2]. - In the A-share market, the innovative drug sector also performed strongly, with Haichen Pharmaceutical hitting a 20% limit up and multiple companies like Zhongsheng Pharmaceutical and Huason Pharmaceutical also reaching their limits [3]. Group 2: ASCO Annual Meeting Highlights - Several companies announced their participation in the ASCO annual meeting, including: 1. BeiGene will present 23 abstracts focusing on new data for its product portfolio in hematological and solid tumor treatments [3]. 2. Kelun-Biotech will share results from six clinical studies, including data on its ADC and PD-L1 monoclonal antibody [4]. 3. Ascentage Pharma will present the latest clinical data on APG-2575 and APG-115 [4]. 4. Legend Biotech will disclose updates on its CARVYKTI clinical development project for multiple myeloma [4]. 5. Hengrui Medicine will present updated data on several of its compounds [4]. Group 3: Future Outlook - Analysts predict that 2025 will mark a pivotal year for the pharmaceutical industry, characterized as the "three milestone years": a year of revenue growth post-medical insurance negotiations, a year of profitability for many companies, and a year of valuation uplift due to improved payment conditions [6]. - The Chinese innovative drug sector is transitioning from being followers to becoming significant players in the international market, with a notable increase in the number of innovative drugs developed by Chinese companies, reaching 3,575 by the end of 2024, surpassing the U.S. [6]. Group 4: Investment Recommendations - Analysts recommend focusing on Hong Kong innovative drug stocks due to several factors: 1. The potential for excess returns as companies establish global competitive advantages [7]. 2. The increasing global competitiveness of Chinese innovative drugs, particularly through licensing agreements [7]. 3. Favorable policy and regulatory changes that support the sector [7]. 4. Financial performance indicators show steady revenue growth and relatively safe valuation levels compared to other growth sectors [7].

金十数据5月23日讯，港股早盘震荡走高，恒指收涨0.58%，报23679.99点；科指收涨0.61%，报5283.69 点。盘面上，药品股领涨，影视出版板块涨幅居前，汽车股分化，黄金股走低，零售商板块下跌。个股 方面，叮当健康(09886.HK)涨15.6%，阿里影业(01060.HK)涨11%，中手游(00302.HK)、昭衍新药 (06127.HK)涨超10%，阅文集团(00772.HK)涨6.6%，哔哩哔哩(09626.HK)涨5.4%，比亚迪股份 (01211.HK)涨3.9%；周大福(01929.HK)跌4.5%，滔搏(06110.HK)跌9.7%。新股Mirxes-B(02629.HK)涨 27.9%，新股恒瑞医药(01276.HK)涨30.87%。中国卫生集团(00673.HK)复牌涨157%，折让28.6%配股引 入新投资者。 港股午评：新股表现亮眼 恒瑞医药涨超30% ...