UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36544 Sage Therapeutics, Inc. (Exact Name of Registrant as Specified in its Charter) (State or Other Jurisdiction of Incorporation o ...

J.P. Morgan Healthcare Conference January 2022 Safe Harbor Statement • The slides presented today and the accompanying oral presentations contain forward-looking statements, which may be identified by the use of words such as "may," "might," "will," "should," "can,","expect," "plan," "anticipate," "believe," "estimate," "project," "intend," "future," "opportunity", "goal", "mission", "potential," "target", or "continue," and other similar expressions. • Forward-looking statements in this presentation includ ...

Investor Presentation November 2021 Safe Harbor Statement • The slides presented today and the accompanying oral presentations contain forward-looking statements, which may be identified by the use of words such as "may," "might," "will," "should," "can,","expect," "plan," "anticipate," "believe," "estimate," "project," "intend," "future," "opportunity", "goal", "mission", "potential," "target", or "continue," and other similar expressions. • Forward-looking statements in this presentation include statement ...

SAGE Therapeutics, Inc. (NASDAQ:SAGE) Q3 2021 Results Earnings Conference Call November 2, 2021 8:00 AM ET Company Participants Helen Rubenstein - Investor Contact Barry Greene - Chief Executive Officer Steve Kanes - Chief Medical Officer Jim Doherty - Chief Research Officer Kimi Iguchi - Chief Financial Officer Conference Call Participants Ritu Baral - Cowen and Company Thomas Deal - J.P. Morgan Paul Matteis - Stifel Financial Yasmeen Rahimi - Piper Sandler Ami Fadia - Needham & Company Andrea Tan - Goldma ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36544 Sage Therapeutics, Inc. (Exact name of registrant as specified in its Charter) (State or other jurisdiction of incorp ...

SAGE Therapeutics, Inc. (NASDAQ:SAGE) Q2 2021 Earnings Conference Call August 3, 2021 8:00 AM ET Company Participants Jeff Boyle - Investor Contact Barry Greene - President, CEO & Director Stephen Kanes - Chief Medical Officer Kimi Iguchi - CFO & Treasurer Conference Call Participants Paul Matteis - Stifel, Nicolaus & Company Tazeen Ahmad - Bank of America Merrill Lynch Yasmeen Rahimi - Piper Sandler & Co. Laura Chico - Wedbush Securities Jay Olson - Oppenheimer Sumant Kulkarni - Canaccord Genuity Operator ...

Investor Presentation August 2021 Safe Harbor Statement • The slides presented today and the accompanying oral presentations contain forward-looking statements, which may be identified by the use of words such as "may," "might," "will," "should," "can,","expect," "plan," "anticipate," "believe," "estimate," "project," "intend," "future," "opportunity", "goal", "mission", "potential," "target", or "continue," and other similar expressions. • Forward-looking statements in this presentation include statements ...

☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-36544 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR Sage Therapeutics, Inc. (Exact name of registrant as specified in its Charter) (State or other jurisdiction of incorporati ...

SAGE Therapeutics, Inc. (NASDAQ:SAGE) Q1 2021 Earnings Conference Call May 4, 2021 8:00 AM ET Company Participants Jeff Boyle - Investor Contact Barry Greene - President, CEO & Director Stephen Kanes - Chief Medical Officer Kimi Iguchi - CFO & Treasurer Jim Doherty - Chief Research Officer Conference Call Participants Andrew Tsai - Jefferies Ritu Baral - Cowen and Company Tazeen Ahmad - Bank of America Merrill Lynch Yasmeen Rahimi - Piper Sandler & Co. Turner Kufe - JPMorgan Chase & Co. Laura Chico - Wedbus ...

Investor Presentation May 2021 Safe Harbor Statement • The slides presented today and the accompanying oral presentations contain forward-looking statements, which may be identified by the use of words such as "may," "might," "will," "should," "can,","expect," "plan," "anticipate," "believe," "estimate," "project," "intend," "future," "opportunity", "goal", "mission", "potential," "target", or "continue," and other similar expressions. • Forward-looking statements in this presentation include statements reg ...