Group 1: Company Overview - Wave Life Sciences (WVE) currently holds a Momentum Style Score of B and a Zacks Rank of 2 (Buy) [1][2] - The company has seen significant price increases, with shares up 77.82% over the past week and 81.07% over the past month [3] - Over the last quarter, WVE shares have increased by 126.07%, and by 165.29% over the past year, outperforming the S&P 500's gains of 5.5% and 40.28% respectively [3] Group 2: Market Performance - The Zacks Medical - Biomedical and Genetics industry has only increased by 2.24% over the past week and 1.44% over the past month, indicating WVE's strong relative performance [3] - WVE's average 20-day trading volume is 2,990,580 shares, which is a bullish indicator when combined with rising stock prices [3] Group 3: Earnings Outlook - In the past two months, 2 earnings estimates for WVE have moved higher, while none have moved lower, resulting in an increase in the consensus estimate from -$1.05 to -$1.01 [4] - For the next fiscal year, 3 estimates have been revised upwards with no downward revisions, indicating positive sentiment around future earnings [4]

Shares of Wave Life Sciences (WVE) surged 74.1% on Wednesday after the company reported positive proofof-mechanism data from an ongoing early to mid-stage study of its investigational candidate, WVE-006, for alpha-1 antitrypsin deficiency (AATD), a type of genetic disorder. WVE-006 is a GalNAc-conjugated oligonucleotide that enables A-to-I RNA editing and is administered subcutaneously. Developed with Wave Life Sciences' advanced oligonucleotide chemistry platform, it is specifically designed to target lung ...

Company Overview - Wave Life Sciences (WVE) shares increased by 74.1% to close at $14.90, with notable trading volume compared to typical sessions, and a 49.9% gain over the past four weeks [1][2] - The stock's rise followed the announcement of positive proof-of-mechanism data from the phase Ib/IIa RestorAATion-2 study of WVE-006 for alpha-1 antitrypsin deficiency, indicating the first-ever therapeutic RNA editing in humans [2] Financial Performance - The company is expected to report a quarterly loss of $0.28 per share, reflecting a year-over-year change of -500%, with revenues projected at $15.45 million, down 68.6% from the previous year [3] - The consensus EPS estimate for the quarter has been revised 9.4% higher over the last 30 days, indicating a potential for price appreciation [4] Industry Context - Wave Life Sciences operates within the Zacks Medical - Biomedical and Genetics industry, where another company, Bristol Myers Squibb (BMY), closed 1.2% higher at $53.37, with a 6.6% return over the past month [4] - Bristol Myers' consensus EPS estimate has changed by +0.4% to $1.52, representing a -24% change compared to the previous year, and currently holds a Zacks Rank of 3 (Hold) [5]

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CAMBRIDGE, Mass., Oct. 16, 2024 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health, today announced it will host a virtual Research Day on Wednesday, October 30, 2024 at 10:00 a.m. ET (until 11:30 a.m. ET). During the event, Wave will provide an update on its rapidly advancing, wholly owned pipeline, introduce new GalNAc-conjugated RNA editing and siRNA programs, and discuss its ...

CAMBRIDGE, Mass., Oct. 01, 2024 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health, announced today that it closed its previously announced underwritten public offering, and that the underwriters exercised in full their option to purchase an additional 3,750,000 of its ordinary shares at the public offering price of $8.00 per ordinary share, less underwriting discounts and commi ...

Shares of Wave Life Sciences (WVE) surged 53.4% on Tuesday after the company announced positive interim data from a mid-stage study evaluating its investigational candidate, WVE-N531, to treat boys with Duchenne muscular dystrophy (DMD) who are amenable to exon 53 skipping. WVE-N531, an exon skipping oligonucleotide, is currently being developed as a disease-modifying treatment for DMD indication in boys. The candidate enjoys the FDA's Orphan Drug and Rare Pediatric Disease designations in the United States ...

CAMBRIDGE, Mass., Sept. 24, 2024 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health, announced today that it has commenced an underwritten public offering of $175 million in aggregate of its ordinary shares, and, to certain investors that so choose in lieu of ordinary shares, pre-funded warrants to purchase ordinary shares. In connection with the offering, Wave intends to grant ...

Mean muscle content-adjusted dystrophin expression of 9.0% and unadjusted dystrophin of 5.5%, with high consistency across participants, in a prespecified analysis; dystrophin was comprised of two isoforms consistent with Becker muscular dystrophy patients who display milder disease Data demonstrated meaningful improvement in serum biomarkers for muscle health, with localization of WVEN531 in myogenic stem cells and regeneration of myofibers Skeletal muscle concentrations of ~41,000 ng/g combined with 61-da ...

Wave Life Sciences (WVE) came out with a quarterly loss of $0.25 per share versus the Zacks Consensus Estimate of a loss of $0.16. This compares to loss of $0.20 per share a year ago. These figures are adjusted for non-recurring items. This quarterly report represents an earnings surprise of -56.25%. A quarter ago, it was expected that this biopharmaceutical company would post a loss of $0.18 per share when it actually produced a loss of $0.24, delivering a surprise of -33.33%. Over the last four quarters, ...