Spyre Therapeutics(SYRE) - 2024 Q1 - Quarterly Results

Exhibit 99.1 SPY001, an anti-α4β7 antibody engineered for infrequent, subcutaneous dosing successfully completed a 28- day GLP toxicity study and remains on track to begin first-in-human studies in the second quarter of 2024, with interim proof-of-concept data expected year-end 2024 SPY002, an anti-TL1A antibody designed for enhanced potency to both TL1A monomers and trimers, and extended half-life compared to existing molecules, remains on track to begin first-in-human studies in the second half of 2024 Ra ...