Revenue and Net Loss - Total revenue for the six months ended June 30, 2024, was 17.277million,adecreasefrom22.248 million in the same period in 2023[11] - Net loss for the six months ended June 30, 2024, was 77.540million,comparedto70.638 million in the same period in 2023[11] - Net loss for the six months ended June 30, 2024 was 77.54million,comparedto70.64 million for the same period in 2023[18] - Basic and diluted net loss per share for the six months ended June 30, 2024, was 0.26,comparedto0.24 in the same period in 2023[11] - Basic and diluted net loss per share for Q2 2024 was (0.13),comparedto(0.11) in Q2 2023, with net losses of (36.9million)and(30.5 million) respectively[28] Research and Development Expenses - Research and development expenses for the six months ended June 30, 2024, were 80.214million,downfrom89.120 million in the same period in 2023[11] - Stock-based compensation expense increased to 35.19millionforthesixmonthsendedJune30,2024,upfrom31.87 million in the same period in 2023[18] - Stock-based compensation expense increased from 16.4millioninQ22023to17.8 million in Q2 2024, primarily driven by R&D and G&A expenses[49] Cash and Marketable Securities - Total cash, cash equivalents, and marketable securities as of June 30, 2024, were 670.356million,adecreasefrom760.585 million as of December 31, 2023[10] - Cash and cash equivalents and restricted cash decreased to 175.60millionasofJune30,2024,comparedto207.04 million as of June 30, 2023[18] - Proceeds from marketable securities increased to 539.39millionforthesixmonthsendedJune30,2024,comparedto422.81 million in the same period in 2023[18] - The company's marketable securities totaled 522.044millionasofJune30,2024,with72.434 million in Level 1 and 449.610millioninLevel2[60]−Thecompany′smarketablesecuritieshadaweightedaveragelifeofapproximately0.6yearsandwereratedA−orhigherbyatleasttwomajorratingagencies[58]AssetsandLiabilities−TotalcurrentassetsasofJune30,2024,were771.554 million, down from 871.985millionasofDecember31,2023[10]−TotalliabilitiesasofJune30,2024,were301.513 million, a decrease from 335.776millionasofDecember31,2023[10]−Totalshareholders′equityasofJune30,2024,was1.110968 billion, down from 1.152318billionasofDecember31,2023[10]−Totalshareholders′equitydecreasedto1.11 billion as of June 30, 2024, down from 1.15billionasofDecember31,2023[15]−Accumulatedothercomprehensivelossincreasedto2.07 million as of June 30, 2024, compared to 1.72millionasofDecember31,2023[15]−Commonsharesoutstandingincreasedto294.67millionasofJune30,2024,upfrom290.82millionasofDecember31,2023[15]−Propertyandequipment,netincreasedfrom287.7 million in December 2023 to 318.9millioninJune2024,drivenbybuildingandleaseholdimprovements[31]−Thecompanyheld32.3 million in non-marketable securities as of June 2024, unchanged from December 2023[52] Depreciation, Amortization, and Impairment - Depreciation, amortization, and impairment expenses for the six months ended June 30, 2024, were 41.366million,upfrom11.124 million in the same period in 2023[11] - Amortization and impairment of intangible assets significantly increased to 34.76millionforthesixmonthsendedJune30,2024,comparedto5.31 million in the same period in 2023[18] - The company recorded a full impairment charge of 32.0 million for IPR&D assets acquired through the TetraGenetics acquisition in 2021[33] - Amortization expense on intangible assets is estimated to be 4.3 million annually from 2025 to 2029, totaling 21.5millionoverfiveyears[35]CashFlowandInvestments−Netcashusedinoperatingactivitiesincreasedto71.67 million for the six months ended June 30, 2024, compared to 24.16millioninthesameperiodin2023[18]−Purchasesofpropertyandequipmentincreasedto44.25 million for the six months ended June 30, 2024, up from 42.19millioninthesameperiodin2023[18]−Thecompany′sequityinvestmentinDayhuJVincreasedslightlyfrom42.1 million in December 2023 to 42.2millioninJune2024[37]−LoanreceivablefromBeedieJVpartnerincreasedsignificantlyfromCAD18.4 million (13.9million)inDecember2023toCAD30.6 million (22.4million)inJune2024[40]GovernmentFundingandContributions−ThecompanyreceivedatotalofCAD175.6 million (125.6million)fromtheCanadiangovernmentundertheStrategicInnovationFund(SIF)forCOVID−19antibodyresearchanddevelopment[63]−Thecompanyenteredintomulti−yearcontributionagreementstotalingCAD300.0 million (222.3million)withtheCanadianandBritishColumbiagovernmentsforantibodymedicinedevelopmentandmanufacturing[64]−ThecompanyrecordedCAD46.0 million (34.1million)inrespectoftheCanadiangovernment′sfundingcommitmentasofJune30,2024[65]−ThecompanyrecordedCAD31.0 million (23.0million)inrespectoftheBritishColumbiagovernment′sfundingcommitmentasofJune30,2024[65]−GovernmentContribution1and2totaled131.593 million on the consolidated balance sheets as of June 30, 2024[67] Contingent Consideration and Liabilities - Contingent consideration related to business acquisitions is measured using Level 3 inputs, with no changes to valuation techniques since acquisition[55] - Trianni's contingent consideration liability increased by 374,000to20.027 million for the three months ended June 30, 2024[56] - TetraGenetics' contingent consideration liability decreased by 32.4millionto4.441 million for the three months ended June 30, 2024[56] Deferred Revenue and Other Financial Metrics - Deferred revenue decreased from 27.2millioninDecember2023to14.4 million in June 2024, with $13.0 million recognized as revenue in H1 2024[50] - The company's exposure to market risk has not changed materially since December 31, 2023[125]