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Nautilus Biotechnology(NAUT) - 2024 Q3 - Quarterly Report

Financial Performance - The net loss for the nine months ended September 30, 2024 was 53,186thousand,comparedtoanetlossof53,186 thousand, compared to a net loss of 46,651 thousand for the same period in 2023, representing an increase of approximately 14%[14]. - For the three months ended September 30, 2024, Nautilus Biotechnology reported a net loss of 16.446million,comparedtoanetlossof16.446 million, compared to a net loss of 15.878 million for the same period in 2023, reflecting an increase in losses of approximately 3.6%[18]. - The company reported total operating expenses of 61,496thousandfortheninemonthsendedSeptember30,2024,comparedto61,496 thousand for the nine months ended September 30, 2024, compared to 56,151 thousand for the same period in 2023, an increase of approximately 9.5%[14]. - Cash used in operating activities for the nine months ended September 30, 2024, was 44.836million,comparedto44.836 million, compared to 37.811 million for the same period in 2023, indicating an 18.4% increase in cash outflow[22]. Assets and Liabilities - Total current assets decreased from 176,837thousandasofDecember31,2023to176,837 thousand as of December 31, 2023 to 144,205 thousand as of September 30, 2024, a decline of approximately 18.4%[11]. - Cash and cash equivalents decreased from 19,397thousandasofDecember31,2023to19,397 thousand as of December 31, 2023 to 4,409 thousand as of September 30, 2024, a decrease of approximately 77.3%[11]. - Total liabilities decreased from 40,212thousandasofDecember31,2023to40,212 thousand as of December 31, 2023 to 36,270 thousand as of September 30, 2024, a reduction of approximately 9.7%[12]. - The company’s total stockholders' equity decreased from 265,353thousandasofDecember31,2023to265,353 thousand as of December 31, 2023 to 223,434 thousand as of September 30, 2024, a decline of approximately 15.8%[13]. Accumulated Deficit - The company’s accumulated deficit increased from 202,239thousandasofDecember31,2023to202,239 thousand as of December 31, 2023 to 255,425 thousand as of September 30, 2024, an increase of approximately 26.3%[13]. - The company had an accumulated deficit of 255.425millionasofSeptember30,2024,comparedto255.425 million as of September 30, 2024, compared to 185.215 million as of September 30, 2023, representing an increase in the deficit of approximately 37.8%[19]. Research and Development - Research and development expenses for the three months ended September 30, 2024 were 12,288thousand,comparedto12,288 thousand, compared to 11,996 thousand for the same period in 2023, reflecting an increase of 2.4%[14]. - The company has been focused on research and development activities related to its proteomics platform since its incorporation in 2016[24]. Stock and Equity - The weighted-average shares used in computing net loss per share attributable to common stockholders for the nine months ended September 30, 2024 was 125,302,440, compared to 124,896,975 for the same period in 2023[14]. - The company issued 367,813 shares of common stock upon the exercise of vested stock options during the nine months ended September 30, 2024, raising 415,000[22].Thetotaladditionalpaidincapitalincreasedto415,000[22]. - The total additional paid-in capital increased to 478.115 million as of September 30, 2024, from 464.509millionasofSeptember30,2023,markinganincreaseofapproximately2.6464.509 million as of September 30, 2023, marking an increase of approximately 2.6%[19]. - The total potentially dilutive common share equivalents increased to 17,484,880 from 14,710,602 year-over-year[84]. Cash and Investments - Nautilus Biotechnology's cash, cash equivalents, and restricted cash at the end of the period on September 30, 2024, was 5.411 million, down from 75.106millionattheendofSeptember30,2023,adecreaseofapproximately92.875.106 million at the end of September 30, 2023, a decrease of approximately 92.8%[22]. - As of September 30, 2024, the company had cash, cash equivalents, and investments totaling 221.2 million[139]. - The carrying amount of cash equivalents approximates fair value due to short maturities of these instruments[139]. Risks and Future Financing - The company may require additional equity or debt financing in the future, depending on growth rate and research and development spending[30]. - The company is subject to risks similar to pre-clinical stage companies in the biopharmaceutical industry, including dependence on key individuals and the need for adequate financing[34]. - The company is exposed to inflation risk, which has impacted labor and goods costs, potentially affecting future operational expenses[140]. Accounting and Reporting - The company is evaluating the impact of new accounting standards on its consolidated financial statements, including ASU 2023-07 and ASU 2023-09[50][51]. - The company’s estimates and assumptions in financial reporting may differ from actual results, impacting future financial statements[31]. - The company had no income tax expense or benefit recognized for the three and nine months ended September 30, 2024, due to a full valuation allowance against deferred tax assets[61].