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Aligos Therapeutics(ALGS) - 2024 Q3 - Quarterly Results

Financial Performance - Aligos reported a net loss of 19.3millionforQ32024,withabasicanddilutednetlosspershareof19.3 million for Q3 2024, with a basic and diluted net loss per share of (3.07), compared to a net loss of 18.0millionand18.0 million and (10.37) per share in Q3 2023[7]. - Cash, cash equivalents, and investments totaled 74.9millionasofSeptember30,2024,downfrom74.9 million as of September 30, 2024, down from 135.7 million as of December 31, 2023, indicating a decrease of approximately 44.8%[6]. - Total operating expenses for Q3 2024 were 21.4million,comparedto21.4 million, compared to 22.3 million in Q3 2023, indicating a slight decrease[15]. - Aligos believes its current cash balance is sufficient to fund planned operations through the end of 2025[6]. Research and Development - Research and development (R&D) expenses increased to 16.8millioninQ32024from16.8 million in Q3 2024 from 15.9 million in Q3 2023, primarily due to higher third-party expenses for clinical trials[8]. - Aligos is progressing ALG-000184 for chronic hepatitis B (CHB) towards a Phase 2 study next year, with positive feedback from the FDA regarding its primary efficacy endpoint[3]. - The company expects to begin externally funded clinical studies for ALG-097558 in COVID subjects later this year, with three additional clinical studies planned for 2024[5]. Clinical Trial Results - The company announced positive topline HERALD data for ALG-055009, showing placebo-adjusted median relative reductions in liver fat of up to 46.2%[2]. - Up to 70% of subjects treated with ALG-055009 achieved a ≥30% relative reduction in liver fat compared to baseline[4]. General and Administrative Expenses - General and administrative (G&A) expenses decreased to 4.6millioninQ32024from4.6 million in Q3 2024 from 6.4 million in Q3 2023, reflecting a reduction in third-party expenses including legal costs[9].