Financial Performance - The net loss for Q3 2024 was 0.36 per share, compared to a net loss of 0.34 per share, in the previous quarter[17]. - Research and development (R&D) expenses for Q3 2024 were 30.7 million in the previous quarter, primarily due to higher manufacturing expenses[16]. - General and administrative (G&A) expenses rose to 7.4 million in the preceding quarter, driven by increased personnel-related costs[17]. Cash and Assets - As of September 30, 2024, cash, cash equivalents, and marketable securities totaled approximately 492,536 thousand, an increase of 54.6% from 511,282 thousand as of September 30, 2024, up from 488,877 thousand, up 53.3% from 22,405 thousand from $21,205 thousand, reflecting a growth of 5.6%[22]. Clinical Trials - The CANYON Phase 2 trial for sevasemten in adults with Becker is set to report data in December 2024, involving 40 adults and 29 adolescents over a 12-month treatment period[4]. - The GRAND CANYON trial, an expansion of the CANYON trial, will evaluate the safety and efficacy of sevasemten in 120 adults over 18 months, with data potentially supporting a marketing application[5]. - The LYNX Phase 2 trial in boys with Duchenne is planned to report data in Q4 2024, guiding the design of a Phase 3 trial expected to start in 2025[8]. - In the Phase 1 trial of EDG-7500, no clinically meaningful changes in vital signs or LVEF were observed across a range of doses, indicating good tolerability[11]. - The CIRRUS-HCM trial reported a 67% mean reduction in resting left ventricular outflow tract pressure gradient with a single dose of EDG-7500, without significant changes in LVEF[12]. Community Engagement - The company continues to engage with the scientific and patient communities, participating in major events for Becker and muscular dystrophy awareness[14].
Edgewise Therapeutics(EWTX) - 2024 Q3 - Quarterly Results