Financial Performance - The net loss for the quarter ended September 30, 2024, was 10.5million,or0.08 per share, compared to a net loss of 10.0million,or0.08 per share, for the same period in 2023[8] - The net loss for the nine months ended September 30, 2024, was 34.3million,or0.25 per share, compared to a net loss of 29.1million,or0.23 per share, for the same period in 2023[8] Research and Development - Research and Development (R&D) expenses for the quarter were 8.6million,aslightdecreasefrom8.8 million in the same period in 2023[9] - Clinical costs related to the COMPANION-002 trial increased by 5.2 million, contributing to the overall rise in R&D expenses for the nine months ended September 30, 2024[9] - The Phase 2/3 trial of CTX-009 in patients with biliary tract cancers is fully enrolled, with top-line data readout expected by the end of Q1 2025[1] - A Phase 2 trial of CTX-009 in combination with chemotherapy for DLL4-positive colorectal cancer is being designed, with initiation expected in mid-2025[1] - CTX-471 has shown a correlation between NCAM (CD56) expression and disease control, leading to plans for a Phase 2 trial in mid-2025[1] - The second dosing cohort of the Phase 1 study of CTX-8371 is fully enrolled, with enrollment into the third cohort expected to begin soon[6] Expenses - General and Administrative (G&A) expenses increased to 3.6 million for the quarter, up from 3.1millioninthesameperiodin2023,primarilyduetohigherstockcompensationexpenses[10]CashandSecurities−CashandmarketablesecuritiesasofSeptember30,2024,totaled135 million, down from 152millionasofDecember31,2023,providingacashrunwayintothefirstquarterof2027[11]LiabilitiesandEquity−Totalliabilitiesincreasedto10,753 million from 8,337million,reflectingagrowthofapproximately29.3138,398 million from 148,538million,indicatingadeclineofabout6.8149,151 million, down from 156,875million,representingadecreaseofapproximately4.96,320 million[21]