Research and Development Expenses - Research and development expenses decreased by 77,000(7.90.9 million, with 0.6millionallocatedtoHT−001,154,300 to HT-KIT, 18,700toHT−004,and96,500 to HT-ALZ[135] - Research and development expenses decreased by 635,700(24.81.9 million, with 1.2millionallocatedtoHT−001,112,800 to HT-ALZ, 363,300toHT−KIT,and96,100 to HT-004[142] General and Administrative Expenses - General and administrative expenses increased by 116,100(10.4473,500 (13.8%) for the nine months ended September 30, 2024 compared to the same period in 2023[144] Net Loss - Net loss for the three months ended September 30, 2024 was 2.1million,adecreaseof45,500 compared to the same period in 2023[141] - Net loss for the nine months ended September 30, 2024 was 5.8million,adecreaseof0.3 million compared to the same period in 2023[150] Cash and Capital Resources - As of September 30, 2024, the company had 8.0millionincashandcashequivalentsandworkingcapitalof7.4 million[151] - The company issued 2,500,000 shares of common stock for net proceeds of 3.8millionduringtheninemonthsendedSeptember30,2024[152]−Issuednewunregisteredwarrantstopurchaseupto3,750,000sharesofcommonstockat1.50 per share, expiring on July 3, 2028[154] - Potential milestone payments of up to approximately 10.5millionifallmilestonesincurrentagreementsareachieved[155]−NetcashusedinoperationsfortheninemonthsendedSeptember30,2024,wasapproximately5.0 million, primarily due to a net loss of 5.8million[157]−NetcashprovidedbyfinancingactivitiesfortheninemonthsendedSeptember30,2024,wasapproximately3.7 million, resulting from net proceeds from the exercise of warrants[159] - Net cash provided by financing activities for the nine months ended September 30, 2023, was approximately $11.3 million, from the issuance of common stock and warrants[160] Stock-Based Compensation and Valuation - The company estimates the fair value of stock option grants using the Black-Scholes option pricing model, involving inherent uncertainties and management's judgment[164] - Restricted stock awards vest over a service period of zero to three years, with stock-based compensation expense recognized on a straight-line basis[167] - Warrants issued to non-employees vest over a term of zero to ten years, with stock-based compensation expense recognized on a straight-line basis[168] Accounting Standards and Disclosures - The company is evaluating the impact of ASU 2023-09 on income tax disclosures, effective for annual periods beginning after December 15, 2024[171] - The company has a single reportable segment and is evaluating the impact of ASU 2023-07 on segment reporting disclosures, effective for fiscal years beginning after December 15, 2023[175]