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Cellectis(CLLS) - 2024 Q3 - Quarterly Report

Financial Performance - Total revenues and other income for the nine-month period ended September 30, 2024, increased to 34,052,000,comparedto34,052,000, compared to 7,203,000 for the same period in 2023, representing a significant growth[7]. - The net loss attributable to shareholders for the nine-month period ended September 30, 2024, was 42,683,000,comparedtoanetlossof42,683,000, compared to a net loss of 66,648,000 for the same period in 2023, reflecting a reduction in losses[7]. - The basic net loss per share attributable to shareholders for the nine-month period ended September 30, 2024, was (0.49),comparedto(0.49), compared to (1.09) for the same period in 2023[7]. - For the nine-month period ended September 30, 2023, net income was a loss of 66,648thousand,comparedtoalossof66,648 thousand, compared to a loss of 42,683 thousand in 2024, reflecting a significant decline[8]. - The company reported a comprehensive income loss of 41.156millionfortheninemonthperiodendedSeptember30,2024[13].ThenetlossfortheninemonthperiodendedSeptember30,2024,was41.156 million for the nine-month period ended September 30, 2024[13]. - The net loss for the nine-month period ended September 30, 2024, was 42.683 million, compared to a net loss of 59.264millionforthesameperiodin2023[13].CashandLiquidityCashandcashequivalentsasofSeptember30,2024,amountedto59.264 million for the same period in 2023[13]. Cash and Liquidity - Cash and cash equivalents as of September 30, 2024, amounted to 159,087,000, an increase from 136,708,000asofDecember31,2023[6].CashandcashequivalentsattheendoftheperiodfortheninemonthperiodendedSeptember30,2023,were136,708,000 as of December 31, 2023[6]. - Cash and cash equivalents at the end of the period for the nine-month period ended September 30, 2023, were 67,358 thousand, increasing to 159,087thousandin2024,indicatingimprovedliquidity[11].Cashandcashequivalentsstoodat159,087 thousand in 2024, indicating improved liquidity[11]. - Cash and cash equivalents stood at 159.1 million, with an additional deposit of 100.3million,providingsufficientfundstosupportoperationsinto2027[20].ResearchandDevelopmentResearchanddevelopmentexpensesfortheninemonthperiodendedSeptember30,2024,were100.3 million, providing sufficient funds to support operations into 2027[20]. Research and Development - Research and development expenses for the nine-month period ended September 30, 2024, were 69,670,000, up from 62,690,000in2023,indicatinganincreaseofapproximately11.562,690,000 in 2023, indicating an increase of approximately 11.5%[7]. - Research and development expenses increased to 69.7 million for the nine-month period ended September 30, 2024, up from 62.7millionin2023,reflectingariseofapproximately11.962.7 million in 2023, reflecting a rise of approximately 11.9%[48]. - Research and development expenses for the three-month period ended September 30, 2023, were 19,075 thousand, increasing to 23,829thousandin2024,indicatingariseininvestmentininnovation[9].ThetotalresearchanddevelopmentexpensesforQ32024were23,829 thousand in 2024, indicating a rise in investment in innovation[9]. - The total research and development expenses for Q3 2024 were 23,829 million, reflecting a significant investment in innovation and product development[52]. Assets and Liabilities - Total assets increased to 395,876,000asofSeptember30,2024,comparedto395,876,000 as of September 30, 2024, compared to 334,270,000 as of December 31, 2023, showing a growth of approximately 18.4%[6]. - Total current liabilities increased to 165,650,000asofSeptember30,2024,from165,650,000 as of September 30, 2024, from 155,144,000 as of December 31, 2023, representing a rise of about 6.5%[6]. - Non-current financial liabilities increased to 61,575,000asofSeptember30,2024,from61,575,000 as of September 30, 2024, from 49,125,000 as of December 31, 2023, reflecting an increase of about 25.3%[6]. - Total financial liabilities increased from 135,151thousandasofDecember31,2023to135,151 thousand as of December 31, 2023 to 141,003 thousand as of September 30, 2024[91]. - Total deferred revenues and contract liabilities increased by 11.7millionto11.7 million to 122.0 million from 110.3millionasofDecember31,2023,primarilyduetoadditionalinvoicingrelatedtothreeResearchPlans[108].ShareholderEquityTotalshareholdersequityincreasedto110.3 million as of December 31, 2023, primarily due to additional invoicing related to three Research Plans[108]. Shareholder Equity - Total shareholders' equity increased to 129,424,000 as of September 30, 2024, from 84,695,000asofDecember31,2023,indicatingagrowthofapproximately52.784,695,000 as of December 31, 2023, indicating a growth of approximately 52.7%[6]. - As of September 30, 2024, Cellectis reported total shareholders' equity of 129.424 million, an increase from 76.123millionasofSeptember30,2023[13].Thesharecapitalincreasedto76.123 million as of September 30, 2023[13]. - The share capital increased to 5.9 million as of September 30, 2024, from 4.4millionasofJanuary1,2024,followingacapitalincreaseinvolvingtheissuanceof28millionsharesfor4.4 million as of January 1, 2024, following a capital increase involving the issuance of 28 million shares for 140.0 million[110]. - Cellectis' share capital increased to 100,093,873 shares as of September 30, 2024, up from 55,583,768 shares as of September 30, 2023[13]. Collaboration and Agreements - Cellectis entered into a Joint Research and Collaboration Agreement with AstraZeneca, aiming to develop up to 10 novel cell and gene therapy products[27]. - AstraZeneca made an initial equity investment of 80million,acquiringapproximately2280 million, acquiring approximately 22% of Cellectis' share capital[28]. - Cellectis received an upfront payment of 25 million under the Joint Research Collaboration Agreement, with potential milestone payments ranging from 70millionto70 million to 220 million for each candidate product[28]. - The total upfront payments allocated to Research Plans amount to 109.1million,including109.1 million, including 25 million from the AZ JRCA and 48.4millionfromtheSubsequentInvestmentAgreement[36].FinancialIncomeandExpensesThecompanyreportedafinancialincomeof48.4 million from the Subsequent Investment Agreement[36]. Financial Income and Expenses - The company reported a financial income of 29,727,000 for the nine-month period ended September 30, 2024, compared to 16,133,000forthesameperiodin2023,markinganincreaseofapproximately84.516,133,000 for the same period in 2023, marking an increase of approximately 84.5%[7]. - Financial income for the nine-month period ended September 30, 2024 was 29,727 million, up from 16,133millioninthesameperiodof2023,markinganincreaseof84.516,133 million in the same period of 2023, marking an increase of 84.5%[58]. - Financial expenses increased from 23,085 million in the nine-month period ended September 30, 2023 to 24,049millionin2024,ariseof4.224,049 million in 2024, a rise of 4.2%[58]. - The company reported a foreign exchange gain of 12,424 million in the nine-month period ended September 30, 2023, which decreased to 3,811millionin2024,adeclineof69.43,811 million in 2024, a decline of 69.4%[58]. Stock Options and Compensation - The weighted-average fair value of stock options granted decreased to €1.41 in 2024 from €1.65 in 2023, with expected volatility remaining high at 64.6%-65.2%[113]. - Share-based compensation expense related to stock option awards was 1.8 million for the nine-month period ended September 30, 2024, compared to $2.0 million for the same period in 2023[115]. - The total number of shares outstanding increased to 100,093,873 as of September 30, 2024, reflecting the issuance of shares related to capital increases and employee stock options[110]. - The balance of non-employee warrants as of September 30, 2024, was 359,207, with a weighted-average exercise price of €26.69 and a remaining average useful life of 1.7 years[120].