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Sanofi(SNY) - 2024 Q4 - Annual Report
SNYSanofi(SNY)2025-02-13 18:41

Acquisitions and Divestments - Sanofi entered into a definitive agreement with Recordati for the sale of its global rights to Enjaymo, receiving an upfront payment of 825millionandpotentialmilestonepaymentsofupto825 million and potential milestone payments of up to 250 million based on sales[654]. - In 2023, there were no material divestments reported by Sanofi[655]. - Sanofi completed the acquisition of Inhibrx for 2,035million,with2,035 million, with 1,885 million allocated to in-process development for SAR447537[658][659]. - The acquisition of QRIB Intermediate Holdings, LLC was completed for 1,419million,impactingcashflowswithanetoutflowof1,419 million, impacting cash flows with a net outflow of 1,410 million[662]. - Sanofi acquired Provention Bio, Inc. for approximately 2.8billion,resultinginanetcashoutflowof2.8 billion, resulting in a net cash outflow of 2,722 million[663]. - The acquisition of Amunix Pharmaceuticals, Inc. involved a fixed payment of €970 million and contingent consideration of up to $225 million, with a net cash outflow of €852 million[665]. Financial Performance - Consolidated net sales for the year ended December 31, 2024, amounted to €41,081 million, an increase of 8.6% compared to 2023[692]. - At constant exchange rates, net sales rose by 11.3%, driven mainly by strong performances for Dupixent, Beyfortus, and ALTUVIIIO[692]. - Gross profit for 2024 was €31,081 million, representing 75.7% of net sales, compared to 76.7% in 2023[691]. - Research and development expenses increased to €7,394 million, accounting for 18.0% of net sales, up from 17.2% in 2023[691]. - Operating income for 2024 was €7,252 million, or 17.7% of net sales, compared to 18.4% in 2023[691]. - Net income attributable to equity holders of Sanofi was €5,560 million, representing 13.5% of net sales, compared to 14.3% in 2023[691]. - Basic earnings per share for 2024 was €4.44, an increase from €4.31 in 2023[691]. - Financial expenses decreased to €1,073 million in 2024, down from €1,293 million in 2023[691]. Sales Performance - Dupixent sales reached €13,072 million, with a reported increase of 22.0% and a constant exchange rate increase of 23.1%[697]. - Biopharma segment net sales reached €41,081 million in 2024, up 8.6% on a reported basis and 11.3% at constant exchange rates (CER)[698]. - ALTUVIIIO sales amounted to €682 million, with 90% generated in the United States, driven by patient switches from older treatments[700]. - Nexviazyme/Nexviadyme sales were €667 million, up 61.2% year-on-year, now accounting for 50% of total Pompe franchise sales[701]. - Sarclisa reported sales of €471 million, up 29.7% at CER, with strong growth across all regions[702]. - Rezurock sales reached €470 million, an increase of 51.6% at CER, driven by strong uptake in the US and launch countries[703]. - Cablivi sales were €249 million, up 9.7% at CER, with significant growth in the United States[704]. - Lantus sales increased to €1,628 million, up 20.8% at CER, primarily due to the withdrawal of a competing medicine[707]. - Toujeo sales rose to €1,227 million, reflecting a 13.4% increase at CER, driven by growth in China[708]. - Total hemophilia A franchise sales (ALTUVIIIO + Eloctate) amounted to €1,050 million, representing a 67.8% increase at CER[700]. Tax and Revenue Recognition - Sanofi's revenue recognition policies ensure that revenue from sales is recognized when control over the product is transferred to the customer, in accordance with IFRS 15[668]. - The company recognizes deferred income taxes on tax loss carry-forwards and temporary differences, with deferred tax assets not recognized if it is more likely than not that they will not be realized[684]. Cash Flow and Impact - Sanofi's cash impact from the deconsolidation of EUROAPI was a net cash inflow of €101 million[656]. - The acquisition-related costs for Inhibrx were included in the total acquisition price, reflecting the company's strategy to enhance its rare disease pipeline[659].