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Zoetis(ZTS) - 2024 Q4 - Annual Report

Revenue Breakdown - In 2024, the company's revenue in the United States was 5,074million,with805,074 million, with 80% from companion animal products and 20% from livestock products[13]. - Total international revenue was 4,102 million, with 54% from companion animal products and 46% from livestock products[13]. - Companion animal products represented approximately 68% of total revenue for the year ended December 31, 2024[16]. - Livestock products accounted for approximately 31% of total revenue for the year ended December 31, 2024[17]. - The company's top-selling products, Simparica/Simparica Trio and Apoquel/Apoquel Chewable, contributed approximately 15% and 11% of total revenue, respectively[27]. - The combined contribution of the top five products, including Cytopoint and Librela, was approximately 41% of total revenue in 2024[27]. - The company's total revenue attributable to antibacterials for livestock was approximately 950millionfortheyearendedDecember31,2024[133].Thedivestitureofthemedicatedfeedadditiveproductportfolioisexpectedtodecreasetotalrevenuesattributabletoantibacterialsforlivestock[133].Approximately41950 million for the year ended December 31, 2024[133]. - The divestiture of the medicated feed additive product portfolio is expected to decrease total revenues attributable to antibacterials for livestock[133]. - Approximately 41% of the company's revenue in 2024 was generated in currencies other than the U.S. dollar, primarily in euros, Brazilian real, Australian dollar, British pound, Canadian dollar, and Chinese renminbi[190]. Research and Development - The company is focusing on research and development for new chemical and biopharmaceutical entities, aiming for product lifecycle innovation[20]. - The company incurred R&D expenses of 686 million in 2024, an increase from 614millionin2023and614 million in 2023 and 539 million in 2022, reflecting a commitment to innovation and product development[37]. - The company operates over 300 R&D programs focused on developing solutions for unmet needs in veterinary medicine, diagnostics, and technological innovation[38]. - The company prioritizes R&D spending based on strategic fit, technical feasibility, return on investment, and market needs, ensuring alignment with business objectives[39]. - The company's R&D efforts are crucial for future success, but there is uncertainty regarding the approval and commercial success of new products under development[159]. Regulatory Compliance - The company has established processes and dedicated resources to ensure compliance with regulatory requirements across various jurisdictions[59]. - The company is subject to stringent regulatory oversight in multiple countries, including the U.S., EU, China, Brazil, and Australia, affecting its market operations[70][72][73][74]. - The company actively engages with global regulatory agencies to ensure compliance and adapt to changing regulations in the animal health sector[59]. - The company's regulatory compliance includes post-market surveillance and reporting of product quality defects and adverse events as required by law[60][64]. - The company is committed to compliance with evolving data privacy laws, which could incur significant costs and risks if not adhered to[79]. - The company faces risks related to compliance with environmental, health, and safety laws, which could result in significant costs and operational disruptions[168]. - Changes in laws and regulations, particularly regarding climate change and chemical regulations, could impose additional compliance costs and affect business operations[169][170]. Competition and Market Dynamics - The company faces increased competition from generic products, particularly as patents for key products expire, impacting sales negatively[56]. - The company’s sales of Draxxin have been negatively affected by generic competition in markets where patents have expired[56]. - Sales of Rimadyl chewable and Draxxin products have declined by 40% and 49% respectively in the U.S. due to increased competition from generic alternatives[124]. - The consolidation trend among veterinarians and livestock producers may lead to decreased pricing power for the company[126]. - The company is experiencing competition from lower-priced generic alternatives, which could adversely affect operating results and financial condition[125]. - Changes in distribution channels for companion animal products may negatively impact market share and margins[127]. - Increased regulation and consumer preference for antibiotic-free protein may adversely affect the demand for the company's products[134]. Manufacturing and Operations - The company has a global manufacturing network of 22 sites, with ongoing expansions and a new site purchased outside Atlanta, Georgia, planned for future production[44]. - The company operates a global manufacturing network consisting of 22 manufacturing sites located in 11 countries as of December 31, 2024[153]. - The company experienced challenges in manufacturing certain products during the COVID-19 pandemic, impacting the ability to meet customer demand[154]. - Significant investments are being made in improvements to existing manufacturing facilities and new plants, but these projects are subject to risks of delays and cost overruns[158]. - The company continues to implement efficiency improvement programs in manufacturing and supply chain, including Six Sigma and Lean capabilities[48]. Employee Engagement and Culture - As of December 31, 2024, the company had approximately 13,800 employees worldwide, with about 6,700 in the U.S. and 7,100 in other jurisdictions[81]. - The employee engagement rate was 86% in 2024, maintaining a high engagement rate in the eighties for the last five years[84]. - The global voluntary attrition rate remained stable at 8% in 2024[87]. - The company has implemented comprehensive employee benefits programs, including fully paid parental leave and mental health support, tailored to various regional needs[88]. - The company emphasizes a workplace culture of responsibility and integrity, with an Open Door Policy for communication[83]. - The company has a strong focus on talent recruitment and development, utilizing various programs to attract and retain top industry talent[87]. Financial Position and Debt - As of December 31, 2024, the company had approximately 6.7billionoftotalunsecuredindebtednessoutstanding[204].Thecompanyhasagreementsforamultiyearrevolvingcreditfacilityandacommercialpaperprogram,eachwithacapacityofupto6.7 billion of total unsecured indebtedness outstanding[204]. - The company has agreements for a multi-year revolving credit facility and a commercial paper program, each with a capacity of up to 1.0 billion[204]. - The company may incur substantial additional debt to finance working capital, capital expenditures, investments, or acquisitions, which could intensify risks related to its high level of debt[205]. - The company's ability to make scheduled payments on or refinance its debt obligations depends on its financial condition and operating performance, which are subject to various external factors[207]. - If cash flows and capital resources are insufficient, the company could face liquidity problems and may need to reduce or delay investments or alter its dividend policy[208]. - Repayment of the company's indebtedness will depend on cash flow generation by its subsidiaries, including international ones[209]. - The inability to generate sufficient cash flows to satisfy debt obligations may adversely affect the company's operating results and financial condition[210]. - A change of control could require the company to repurchase outstanding senior notes, but it may not have sufficient funds available at that time[211]. Environmental and Sustainability Concerns - Environmental-related capital expenditures amounted to approximately 5million,whileotherenvironmentalrelatedexpenditurestotaledaround5 million, while other environmental-related expenditures totaled around 23 million[112]. - The company is facing increased regulatory scrutiny regarding the environmental impact of animal health products, which may require additional resources for compliance[105]. - Future capital expenditures for environmental compliance or remediation are currently not expected to materially affect operating results or financial condition[107]. - The company is committed to ongoing expenditures for compliance with environmental, health, and safety laws[105]. - The company's sustainability program includes various ESG goals, but achieving these goals presents numerous operational and reputational risks[180]. Risks and Challenges - The company may face risks related to labor disputes, strikes, or work stoppages, which could disrupt operations and increase costs[149]. - Climate change poses potential risks to the company's operations and those of its customers, affecting livestock health and production[145]. - The company anticipates that new business lines or products may introduce substantial risks and uncertainties[132]. - The introduction of disruptive innovations and alternative products could negatively impact the market for the company's offerings[131]. - The company relies on third-party suppliers for products, materials, and services, which exposes it to increased labor and material costs, potentially impacting operating results and financial condition[156]. - The company is regularly involved in patent litigation and other intellectual property claims, which can be costly and time-consuming[203]. - Counterfeit and illegally compounded products pose a significant risk to the company's reputation and business, particularly in markets like Brazil[174][175]. - Misuse or off-label use of products could lead to increased liability and reputational harm for the company[176]. - The company is exposed to risks from currency fluctuations and potential cash repatriation restrictions, particularly in countries like China[192]. - The company is subject to changes in tax rates and potential additional tax liabilities due to its multinational operations, which could adversely affect its effective tax rate[196]. - The company has experienced lower than expected sales in certain emerging markets due to local restrictions on banking and commercial activities[194]. - The company relies on complex information technology systems for operations, and any system failures could materially adversely affect its financial condition[186]. - The company may face significant costs associated with cybersecurity measures, litigation, and regulatory investigations in the event of a cyberattack[185]. - The company faces significant risks related to compliance with a variety of data privacy laws across multiple jurisdictions, which could result in substantial fines and penalties[179]. - The company has been investing in data and digital capabilities, including AI technologies, which may increase vulnerability to cyberattacks and breaches of security[182].