Financial Performance - Fourth-quarter 2024 total net sales were 667.5million,adecreaseof2.0681.2 million in Q4 2023[4] - Full-year 2024 reported net sales decreased 3.9% to 2,566.5millioncomparedto2,671.2 million in 2023[12] - Bio-Rad reported net sales of 667.5millionforQ42024,adecreaseof2.3681.2 million in Q4 2023[37] - For the full year 2024, Bio-Rad's revenues totaled 2.566billion,downfrom2.671 billion in 2023, marking a decline of 3.9%[37] Segment Performance - Life Science segment net sales for Q4 2024 were 275.0million,adeclineof5.5392.5 million, an increase of 0.9% compared to Q4 2023, primarily due to increased demand for quality control and blood typing products[6] Profitability Metrics - Full-year 2024 gross margin was 53.7%, compared to 53.4% in 2023[14] - Non-GAAP gross margin for full-year 2024 was 55.0%, compared to 54.2% in 2023[17] - GAAP gross profit for Q4 2024 was 342.0million,representing51.2366.3 million and 53.8% in Q4 2023[45] - Non-GAAP gross profit for the year ended December 31, 2024, was 1,411.6million,or55.01,448.3 million and 54.2% in 2023[45] Income and Loss - The company experienced a net loss of 715.8millioninQ42024,comparedtoanetincomeof349.7 million in Q4 2023, resulting in a basic loss per share of 25.57[37]−GAAPnetincomefortheperiodwas(715.8) million, a decrease of 107.2% compared to the previous year[48] - The company reported a significant loss of (1,844.2)millioninGAAPnetincomefortheyear,adecreaseof71.981.2 million, representing a 12.2% margin, while the previous year's figure was 89.3millionwitha13.179.6 million in Q4 2024, up from 63.9millioninQ42023,reflectingagrowthof24.579.6 million, up from 63.9millioninQ42023[46]−Non−GAAPresearchanddevelopmentexpensefortheyearendedDecember31,2024,was281.8 million, compared to 254.8millionin2023[46]−GAAPselling,generalandadministrativeexpenseforQ42024was204.0 million, slightly down from 207.1millioninQ42023[45]−Non−GAAPselling,generalandadministrativeexpensefortheyearendedDecember31,2024,was798.5 million, compared to 814.6millionin2023[45]CashFlowandAssets−Cashandcashequivalentsattheendof2024were488.1 million, an increase from 403.8millionattheendof2023[40]−Totalassetsdecreasedto9.364 billion in 2024 from 12.299billionin2023,adeclineof23.6455.2 million for the year ended December 31, 2024, compared to 374.9millionin2023,anincreaseof21.42.794 billion in 2024 from 3.558billionin2023,areductionof21.511.7 million and restructuring costs of $14.7 million during the reporting period[48]