Revenue and Financial Performance - Total revenues for 2024 reached 9,625million,representinga9.98,757 million in 2023 and a 18.5% increase from 8,124millionin2022[27]−TheSalixsegmentgenerated2,333 million in revenue for 2024, accounting for 24% of total revenues, compared to 2,250million(262,090 million (26%) in 2022[27] - The Bausch + Lomb segment contributed 4,791millioninrevenuefor2024,makingup504,146 million (47%) in 2023 and 3,768million(46616 million, which is approximately 6% of total revenue, compared to 7% in both 2023 and 2022[47] - The company has around 75 R&D projects currently in its pipeline, supported by approximately 1,500 dedicated R&D and quality assurance employees[46] - The company is focused on securing and maintaining third-party research, development, and distribution arrangements to support its product offerings[696] Product Portfolio and Market Strategy - The company has approximately 1,000 products in its portfolio, categorized into five reportable segments[27] - The Xifaxan product accounted for revenues of 1,993millionin2024,upfrom1,810 million in 2023 and 1,692millionin2022[30]−Thecompanyisfocusingonstrategicacquisitionsandlicensingagreementstoenhanceitsproductportfolioandmarketpresence[26]−ThecompanycompletedtheacquisitionofXIIDRAinQ32023,enhancingitseyehealthproductofferings[44]−Thecompanyispursuingacquisitions,includingrecentpurchasesintheophthalmologysector,whichmayincreasedebtlevels[690]RegulatoryandCompliance−Thecompanyissubjecttoextensiveregulationsgoverningtheresearch,development,andmarketingofitsproducts,requiringsignificanttimeandfinancialresources[52]−CompliancewiththeGDPRmayresultinfinesofupto414,552 million in fixed rate debt and 5,929millioninvariableratedebt[632]−Thecompanyhassubstantialdebtobligations,withsignificantamountsduein2025and2026,impactingfinancialflexibility[690]−A140 million[627] - If interest rates were to increase by 100 basis points, the fair value of the company's issued fixed rate debt would decrease by approximately 260million[632]GoodwillandImpairment−Thecompanyrecordedgoodwillimpairmentchargesof493 million in 2023 and 824millionin2022,withnoimpairmentsduring2024[649]−TheDermatologyreportingunitexperiencedagoodwillimpairmentof151 million due to lower realized pricing and revised future expectations, with a long-term growth rate of 0.0% and a discount rate of 10.75% used in the assessment[656] - The Neurology reporting unit recognized a goodwill impairment of 622millionduringthe2022annualimpairmenttestduetochangingmarketdynamicsandincreasedcompetition[660]−TheGenericsreportingunitrecognizedagoodwillimpairmentof91 million as of October 1, 2023, with a long-term growth rate of 1.0% and a discount rate of 10.25% applied in the fair value test[663] Operational Efficiency and Challenges - The company is focused on improving operational efficiency and anticipates a positive impact from these plans[685] - The company expects to continue facing challenges due to ongoing litigation and regulatory investigations, which may affect financial results[686] - The company is actively managing its research and development portfolio, with ongoing evaluations that may lead to project terminations and potential impairment charges[697] - The company is exposed to economic factors such as inflationary pressures, heightened interest rates, and foreign currency rates, which may impact revenues and margins[694] Market Competition and Product Risks - The company faces increased competition from generic pharmaceutical products as patents expire, leading to potential revenue impacts[87] - The company faces risks related to macroeconomic factors, including inflation and potential trade policy changes that could affect operational costs[693] - A substantial amount of the company's revenue is derived from the Xifaxan product line, with potential material impact from the entry of a generic rifaximin product before January 2028[694] - The company faces risks from the introduction of generic, biosimilar, or other competitors to its branded products, which could affect revenue and profits[694] Employee and Workplace Safety - As of December 31, 2024, the company had approximately 20,700 employees, with 10,700 in production and 6,700 in sales and marketing[96] - The Lost Time Incident Rate for the company in 2024 was 1.7 recorded cases per 100 employees, consistent with the industry average[98] - Bausch + Lomb's Days Away Rate (DAR) in 2024 was 4.9, significantly lower than the industry standard DAR of 22[99] Future Outlook and Strategic Plans - The anticipated completion of the B+L Separation is subject to various conditions, including regulatory approvals and market conditions[688] - The company is preparing for potential changes in drug pricing regulations that could affect revenue[688] - The company is exploring plans for its aesthetic medical business, which may influence future growth strategies[698]