Financial Performance - Heron achieved Q4 2024 GAAP Net Income of 3.6million,markingasignificantmilestoneforthecompany[7].−Full−year2024NetRevenuereached144.2 million, representing a 14% increase year-over-year[7]. - ZYNRELEF generated Q4 2024 Net Revenue of 8.5million,withafull−yearrevenueof25.5 million, up 44.1% from 2023[7][9]. - Total Net Revenue for Q4 2024 was 40.8million,a19.140,781 million, a 19.5% increase from 34,233millioninQ42023[29].−GrossprofitforthetwelvemonthsendedDecember31,2024,was105,637 million, compared to 61,939millionin2023,reflectingasignificantimprovement[29].−ThenetlossforQ42024was3,663 million, a substantial improvement from a net loss of 10,724millioninQ42023[29].−Basicanddilutednetincomepershareimprovedto0.02 in Q4 2024, compared to a loss of 0.07pershareinQ42023[29].RevenueGuidanceandExpectations−Thecompanyexpects2025NetRevenueguidancebetween153.0 million and 163.0million,withAdjustedEBITDAguidancerangingfrom0.0 million to 8.0million[5].ProductPerformance−APONVIE′srevenuesurgedby224.84.5 million in 2024[9]. - Acute Care segment revenue increased by 57.3% year-over-year, totaling 30.1millionin2024[9].MarketExpansion−ThepartnershipwithCrosslinkNetworkisexpectedtoenhancepromotionaleffortsforZYNRELEFintheorthopedicsurgerymarket[8].−ExpandedlabelindicationsforZYNRELEFnowcoverapproximately17millionannualtargetedprocedures,significantlyincreasingitsmarketpotential[8].CashandAssets−Cash,cashequivalents,andshort−terminvestmentstotaled59.3 million as of December 31, 2024[8]. - Cash and cash equivalents decreased to 25,802millionasofDecember31,2024,from28,677 million in 2023[31]. - Accounts receivable increased to 78,881millionin2024,upfrom60,137 million in 2023, indicating higher sales volume[31]. - Total assets grew to 233,147millionin2024,comparedto222,506 million in 2023, reflecting overall growth[31]. Liabilities and Deficits - Current liabilities increased to 91,457millionin2024,upfrom79,685 million in 2023, suggesting increased operational commitments[31]. - The accumulated deficit as of December 31, 2024, was (1,919,594)million,slightlyworseningfrom(1,906,014) million in 2023[31]. Cost Management - Total operating expenses decreased to 117,165millionforthetwelvemonthsendedDecember31,2024,downfrom172,554 million in 2023, indicating cost management efforts[29].