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TScan Therapeutics(TCRX) - 2024 Q4 - Annual Results
TCRXTScan Therapeutics(TCRX)2025-03-05 12:15

Revenue Performance - Revenue for Q4 2024 was 0.7million,down90.30.7 million, down 90.3% from 7.2 million in Q4 2023; full-year revenue decreased to 2.8millionfrom2.8 million from 21.0 million in 2023[6]. - Collaboration and license revenue for the three months ended December 31, 2024, was 665million,comparedto665 million, compared to 7,211 million for the same period in 2023[21]. Expenses and Losses - R&D expenses increased to 29.4millioninQ42024,up31.329.4 million in Q4 2024, up 31.3% from 22.4 million in Q4 2023; full-year R&D expenses rose to 107.4millionfrom107.4 million from 88.2 million[9]. - Total operating expenses increased to 37,377millionforthethreemonthsendedDecember31,2024,from37,377 million for the three months ended December 31, 2024, from 28,568 million in the prior year, representing a 30.5% increase[21]. - The net loss for Q4 2024 was 35.8million,comparedto35.8 million, compared to 19.6 million in Q4 2023; full-year net loss increased to 127.5millionfrom127.5 million from 89.2 million[11]. - The net loss for the three months ended December 31, 2024, was 35,809million,comparedtoanetlossof35,809 million, compared to a net loss of 19,613 million for the same period in 2023, indicating an increase of 82.4%[21]. - Total operating expenses for the twelve months ended December 31, 2024, were 137,637million,upfrom137,637 million, up from 114,507 million in 2023, marking a 20.2% increase[21]. - The loss from operations for the twelve months ended December 31, 2024, was 134,821million,comparedto134,821 million, compared to 93,458 million in 2023, indicating a significant increase of 44.3%[21]. - The company reported a net loss of 127,499millionforthetwelvemonthsendedDecember31,2024,comparedtoanetlossof127,499 million for the twelve months ended December 31, 2024, compared to a net loss of 89,218 million in 2023, reflecting an increase of 43%[21]. Cash Position - Cash, cash equivalents, and marketable securities as of December 31, 2024, were 290.1million,sufficienttofundoperationsintoQ12027[12].Thecompanycloseda290.1 million, sufficient to fund operations into Q1 2027[12]. - The company closed a 30 million registered direct offering at a 37% premium, extending its cash runway[6]. Clinical Development - Seven TCR-Ts are now cleared for clinical development in the PLEXI-T Phase 1 trial, including the recently added MAGE-A4 TCR-T[7]. - TScan plans to initiate a registration trial for TSC-101 in the second half of 2025, pending regulatory feedback[7]. - The company aims to present additional data from the Phase 1 trial by the end of 2025, including two-year relapse data[7]. Recognition - TScan has been recognized as one of the Top Places to Work in Massachusetts for the third consecutive year[6].