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Cellectar Biosciences(CLRB) - 2024 Q4 - Annual Results

Financial Performance - Cellectar Biosciences achieved a net loss of 44.6millionor44.6 million or 1.22 per basic share for the year ended December 31, 2024, compared to a net loss of 42.8millionor42.8 million or 3.50 per basic share in 2023[12]. - Other income and expense netted approximately 7.3millionin2024,comparedtoanetexpenseofapproximately7.3 million in 2024, compared to a net expense of approximately 3.9 million in 2023, primarily due to non-cash items related to equity securities[12]. - Total operating expenses for 2024 were approximately 51.8million,comparedto51.8 million, compared to 39.0 million in 2023, reflecting increased costs associated with the company's growth initiatives[18]. Cash Position - Cash and cash equivalents increased to 23.3millionasofDecember31,2024,upfrom23.3 million as of December 31, 2024, up from 9.6 million at the end of 2023, supported by 44.1millionfromwarrantexercisesand44.1 million from warrant exercises and 19.4 million from inducement financing[6]. Research and Development - Research and Development expenses decreased to approximately 26.1millionin2024fromapproximately26.1 million in 2024 from approximately 27.3 million in 2023, primarily due to the timing of expenditures for the WM Phase 2 study[6]. - The company finalized a study design for the potential FDA accelerated approval of iopofosine I 131, with a total study cost expected to be between 40millionand40 million and 45 million[4]. - Cellectar plans to submit an IND application for its alpha-emitting radioconjugate in the first half of 2025, with Phase 1 clinical studies expected to begin by mid-2025[3]. - The company is preparing to initiate a Phase 1b/2a dose-finding study with CLR 121125 in triple-negative breast cancer, targeting significant unmet needs[6]. Clinical Study Results - The Phase 2 CLOVER-WaM study demonstrated an overall response rate (ORR) of 83.6% and a major response rate (MRR) of 58.2%, exceeding the FDA's primary endpoint of 20% MRR[6]. General and Administrative Expenses - General and Administrative expenses rose significantly to approximately 25.6millionin2024fromapproximately25.6 million in 2024 from approximately 11.7 million in 2023, driven by costs related to commercialization infrastructure[6].