
Financial Performance - The company's revenue for 2024 reached RMB 12,260,814, an increase of 21.4% compared to RMB 10,103,806 in 2023[9] - Gross profit for 2024 was RMB 11,155,406, reflecting a gross margin of approximately 91%[9] - The company reported a net profit of RMB 4,371,825 for 2024, up 33.4% from RMB 3,277,503 in 2023[9] - The company recorded a revenue of approximately RMB 12.261 billion for the year ending December 31, 2024, representing a year-on-year growth of about 21.3%[22] - Profit for the same period was approximately RMB 4.372 billion, an increase of about 33.4% compared to the previous year[22] - The company achieved a basic earnings per share of approximately RMB 0.74, reflecting a year-on-year increase of about 33.3%[22] Assets and Liabilities - Total assets as of 2024 amounted to RMB 31,657,849, while total liabilities decreased to RMB 2,977,935[9] - The asset-liability ratio was approximately 9.4% as of December 31, 2024, down from 21.9% the previous year[61] - The company maintained a cash and bank deposit balance of RMB 22.622 billion as of December 31, 2024, compared to RMB 22.435 billion a year earlier[61] Research and Development - Research and development expenses for 2024 were RMB 2,701,650, representing a significant investment in innovation[9] - The company is conducting over 60 clinical trials for innovative drugs, with 8 new candidates entering clinical research stages during the reporting period[38] - The company has established a robust R&D platform with over 1,800 researchers across multiple centers, focusing on innovative drug development[37] - The company plans to continue increasing R&D investments due to market changes and innovation efforts[141] Product Development and Approvals - The company received clinical trial approval for its new drug HS-10501, aimed at treating type 2 diabetes and adult obesity[11] - A licensing agreement was established with Pumis for the global development and commercialization of HS-20117, a bispecific ADC product[11] - The company has submitted multiple New Drug Applications (NDAs) for its innovative drug Amelior, targeting specific NSCLC patient populations[12] - The company received breakthrough therapy designation from the FDA for GSK5764227 (HS-20093) for the treatment of ES-SCLC patients[13] - The company’s innovative drug HS-20110 received clinical trial approval from NMPA for advanced solid tumors[14] - The company’s innovative drugs have all been included in the national medical insurance catalog as of December 31, 2024[24] Market Strategy and Partnerships - The company aims to expand its market presence through strategic partnerships and new product developments in the coming years[11] - The company will continue to focus on innovative drug development and internationalization strategies, particularly in oncology, central nervous system, metabolism, and autoimmune disease treatment areas[82] - The company plans to strengthen business development collaborations to optimize its global market layout[82] Corporate Governance - The board of directors consists of three executive directors and three independent non-executive directors as of December 31, 2024[87] - The company has established five specialized committees within the board to oversee various aspects of governance, including audit and remuneration[85] - The company has adopted a high standard of corporate governance to protect shareholder interests and enhance corporate value[84] Risk Management - The company identified major risks including industry competition and technological changes, emphasizing the need for continuous R&D investment to maintain product competitiveness[74] - Regulatory changes in the Chinese pharmaceutical industry may pose challenges to short-term business operations and cost structures, requiring the company to adapt to new regulations[75] - The company employs risk assessment tools such as risk matrices and sensitivity analysis to scientifically classify risks and implement corresponding control strategies[81] Employee and Talent Management - Attracting and retaining key talent is critical for enhancing organizational capabilities, with established mechanisms for talent retention and training[80] - The group’s employees are considered the most valuable asset, with compensation linked to performance and regular training provided to enhance productivity[153] Environmental, Social, and Governance (ESG) - The company maintained an MSCI ESG rating of AA and ranked first in the S&P Global Corporate Sustainability Assessment for the Chinese pharmaceutical industry[15][17] - The company is committed to identifying and mapping climate risks to its future strategies and business activities, focusing on carbon neutrality goals[81] - The group plans to publish an Environmental, Social, and Governance (ESG) report in conjunction with its annual report, as per listing rules[151] Shareholder Information - The company reported a proposed final dividend of HKD 0.1353 per share for the year ending December 31, 2024, compared to HKD 0.1422 in 2023, resulting in a total annual dividend of HKD 0.3363 per share[132] - As of December 31, 2024, major shareholders include Stellar Infinity and Sunrise Investment, each holding 3,900,000,000 shares, representing 65.70% of the total shares[170] Financial Management - The company has established a robust internal control system and conducted an annual review of its risk management and internal control systems, which the board believes are effective and adequate[121] - The company has adopted a dividend policy that considers its operating performance, cash flow, financial condition, and other relevant factors when declaring dividends[129]