Financial Performance - Total revenue for Q1 2025 was 4.2million,adecreasefrom10.0 million in Q1 2024[7] - Net loss for Q1 2025 was 45.6million,comparedtoanetlossof40.6 million in Q1 2024, resulting in a loss per share of (0.15)[7][16]−NetlossforthethreemonthsendedMarch31,2024,was40,610, compared to a net loss of 45,621 for the same period in 2025[19] Expenses - Research and Development (R&D) expenses increased to 42.5 million in Q1 2025 from 39.3millioninQ12024,reflectinga5.52.8 million in Q1 2025 from 3.4 million in Q1 2024[7] - General & Administrative (G&A) expenses decreased to 16.2 million in Q1 2025 from 17.4millioninQ12024[7]−Cashusedinoperatingactivitieswas41,708 for the three months ended March 31, 2024, significantly higher than 11,554in2025[19]−Stock−basedcompensationwas17,409 for the three months ended March 31, 2024, down from 14,786in2025[19]LiquidityandCashFlow−ThecompanyendedQ12025withover800 million in available liquidity, including 633millionincashandcashequivalents[2][7]−Cashandcashequivalentsandrestrictedcashattheendoftheperiodwere150,862 for March 31, 2024, compared to 186,556forthesamedatein2025[19]−Totalcash,cashequivalents,andrestrictedcashshownonthebalancesheetwas148,572 for March 31, 2024, versus 184,266forthesamedatein2025[19]−Netcashprovidedbyinvestingactivitieswas29,910 for the three months ended March 31, 2024, compared to 7,935in2025[19]OperationalHighlights−Cumulativepartner−initiatedprogramstartswithdownstreamsreached97inQ12025,an824,140 for the three months ended March 31, 2024, compared to 10,636in2025[19]−Proceedsfrommarketablesecuritieswere306,545 for the three months ended March 31, 2024, compared to 190,027in2025[19]−Researchfeesandgrantsreceivableshowedasignificantchangeof(18,576) for the three months ended March 31, 2024, compared to (1,133)in2025[19]−Deferredrevenuechangedby(8,017) for the three months ended March 31, 2024, while it increased by $13,313 in 2025[19]