XORTX Therapeutics (XRTX) - Prospectus(update)

TABLE OF CONTENTS As filed with the U.S. Securities and Exchange Commission on February 12, 2026. Registration No. 333-290512 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 to FORM F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 XORTX THERAPEUTICS INC. (Exact name of registrant as specified in its charter) 2834 (Primary Standard Industrial Classification Code Number) 3710 – 33rd Street NW Calgary, Alberta, Canada T2L 2M1 (403) 455-7727 (Address, including ...