Immunoprecise(IPA) - 2021 Q3 - Quarterly Report

The previously observed high viral clearance efficacy of TATX-03 in SARS-CoV-2-D614G-challenged hamsters implied a concerted action of the respective antibodies. Apart from anti-viral effects resulting from blocking host cell infection via synergistic effects, the demonstrated ability of TATX-03 to simultaneously bind to four different regions of the spike trimer is anticipated to promote viral clearance by the host's immune system. Recently obtained in vitro studies support this role of antibody-mediated c ...