Financial Performance - Total revenues for the three months ended March 31, 2024, were 7,447million,a226,105 million in the same period of 2023[10]. - Product sales reached 7,118million,upfrom5,846 million, reflecting a 22% growth year-over-year[10]. - Operating income decreased to 991millionfrom1,921 million, representing a decline of 48%[10]. - Net loss for the three months ended March 31, 2024, was (113)millioncomparedtoanetincomeof2,841 million in the same period of 2023[10]. - Basic and diluted loss per share for the current period was (0.21),downfromearningsof5.32 and 5.28,respectively,intheprioryear[10].−Thecompanyreportedapretaxlossof68 million for Q1 2024, compared to a pretax income of 3,442millioninQ12023[45].−TheeffectivetaxrateforthethreemonthsendedMarch31,2024,was(66.2)1,343 million from 1,058million,markinga276,456 million, up from 4,184million,indicatinga541,399 million for the quarter, compared to 900millionintheprioryear[23].−Amortizationoffinite−livedintangibleassetsforthethreemonthsendedMarch31,2024,was1.2 billion, compared to 693millionforthesameperiodin2023,indicatingasignificantincreaseofapproximately73.23.6 billion[74]. Cash and Assets - Cash and cash equivalents decreased to 9,708millionfrom10,944 million[15]. - Total assets as of March 31, 2024, were 92,980million,downfrom97,154 million at the end of 2023[15]. - Total inventories decreased to 8,724millionasofMarch31,2024,from9,518 million as of December 31, 2023, a decline of approximately 8.3%[67]. - The fair value of money market mutual funds decreased from 10,266millionasofDecember31,2023,to9,099 million as of March 31, 2024[89]. - The fair value of equity securities decreased from 4,514millionasofDecember31,2023,to3,985 million as of March 31, 2024[89]. Debt and Liabilities - Long-term debt decreased to 60,061millionfrom63,170 million, reflecting a reduction of 5%[15]. - The total carrying value of debt decreased to 64,020millionasofMarch31,2024,from64,613 million as of December 31, 2023[78]. - The company repurchased portions of various notes for an aggregate cost of 410millionduringthethreemonthsendedMarch31,2024,resultingina133 million gain on extinguishment of debt[79]. - Total liabilities as of March 31, 2024, were 1,168million,comparedto1,188 million as of December 31, 2023[89]. Acquisitions - The company completed the acquisition of Horizon Therapeutics for approximately 27.8billion,enhancingitsportfolioinrarediseases[31].−Theacquisitionincludedcashconsiderationof26.7 billion and additional costs related to options and equity awards totaling 523million[33].−Thefairvalueofdeveloped−product−technologyrightsacquiredintheHorizonacquisitionwasestimatedat19,590 million[34]. - The estimated fair value of acquired inventory from Horizon was 5,025million,withamortizationexpectedoverapproximately27months[35].LegalandRegulatoryMatters−Legalproceedingsandinvestigationsmayhaveoutcomesthataredifficulttopredict,potentiallyaffectingthecompany′sfinancialposition[116].−ThecompanyisinvolvedinpatentlitigationconcerningRepathaandotherproducts,withsignificanthearingsscheduledinthecomingyears[118].−Amgen′spatentclaimsrelatedtothe′736PatentwerefoundvalidandenforceablebytheNewJerseyDistrictCourt[121].−Amgensuccessfullydismissedindirectpurchasers′claimsintheantitrustclassactionsinDelawareDistrictCourt[122].MarketandInvestmentRisks−Thecompanyrecognizedanunrealizedlossof454 million on its equity investment in BeiGene for the three months ended March 31, 2024, compared to an unrealized gain of 1.9billionforthesameperiodin2023[60].−ThecarryingvalueoftheequityinvestmentinBeiGenewas3.0 billion as of March 31, 2024, down from 3.4billionasofDecember31,2023[60].−Thecompanyincurrednetchangesinvaluationsofcontingentconsiderationobligationsof2 million for the three months ended March 31, 2024[94].