Financial Performance - The company reported a net loss of 10.3millionforthethreemonthsendedJune30,2024,and18.1 million for the six months ended June 30, 2024, with an accumulated deficit of 121.6millionasofJune30,2024[107].−Thenetlossattributabletoordinaryshareholderswas13.4 million for the six months ended June 30, 2024, a decrease of 41.3million(7618.1 million for the six months ended June 30, 2024, compared to a net loss of 43.8millionforthesameperiodin2023[164][165].−ThenetlossattributabletoOrdinaryShareholdersoftheCompanywas12.7 million for the three months ended June 30, 2024, a decrease of 21.4million(48112.5 million in gross proceeds from the April 2024 Private Placement, issuing 18,732,301 Class A Ordinary Shares and pre-funded warrants[111]. - The company generated approximately 56.7millioninnetproceedsfromtheBusinessCombinationcompletedonMarch20,2023[110].−AsofJune30,2024,thecompanyhadcashandcashequivalentsof188.4 million, funded through various financing activities including a 112.5millionprivateplacement[155].−NetcashprovidedbyfinancingactivitiesforthesixmonthsendedJune30,2024,was105.3 million, a decrease of 15.9% from 125.4millioninthesameperiodof2023[166][167].Expenses−Researchanddevelopmentexpensesdecreasedby22.7 million (80%) to 5.5millionforthethreemonthsendedJune30,2024,primarilyduetoa27.2 million expense related to an IPR&D license acquisition in the prior year[134][136]. - General and administrative expenses increased by 0.5million(106.2 million for the three months ended June 30, 2024, driven by higher compensation and professional fees[137]. - The Company anticipates a substantial increase in research and development expenses as it continues to develop product candidates and manufacturing processes[131]. - General and administrative expenses increased by 2.5million(292.0 million increase in compensation-related expenses[148]. - Total operating expenses decreased by 21.5million(52155.0 million and sales milestone payments of up to 440millionbasedonnetsalesthresholdsforproductsdevelopedfromZB−106[117].−ThecompanyenteredintoalicenseagreementwithLillyfortheexclusiverightstodevelop,manufacture,andcommercializeabispecificantibody,ZB−106,withaninitialpaymentof5.0 million made during the six months ended June 30, 2024[114]. - The company entered into a Lonza License agreement, which includes potential annual payments of up to middle six-figure amounts per sublicense and royalties of up to low-single digit percentages of net sales[169]. - A master services agreement with WuXi Biologics was established in July 2023, obligating the company to pay service fees as specified in each work order[170]. Operational Changes - The company has incurred significant operating losses since inception and anticipates expenses will increase significantly as it advances preclinical and clinical development of product candidates[107]. - The company has a new CEO, Robert Lisicki, effective April 8, 2024, following a transition from founder Someit Sidhu[123]. - The Company commenced an exchange offer for outstanding IPO warrants, offering 0.30 Class A ordinary shares for each warrant tendered[124]. - The Exchange Offer and Consent Solicitation resulted in 6,703,428 public warrants (approximately 97.2%) and 4,080,580 private placement warrants (approximately 69.0%) being validly tendered[125]. - The Company issued 3,235,184 Class A ordinary shares in exchange for 10,784,008 IPO warrants, with a mandatory exchange ratio of 0.27 Class A ordinary shares for each remaining IPO warrant[126]. Economic Impact - Macroeconomic conditions, including geopolitical conflicts and inflation, continue to impact the Company's business and may materially affect future results[127]. - Cash used in operating activities for the six months ended June 30, 2024, was 11.6million,comparedto8.4 million for the same period in 2023, reflecting an increase of 38.1%[164][165]. - Cash used in investing activities for the six months ended June 30, 2024, was 5.0million,slightlylowerthan5.8 million in the same period of 2023[166]. Non-Cash Charges - Non-cash charges for the six months ended June 30, 2024, included 6.7million,primarilyfromshare−basedcompensationof5.3 million[164]. Company Classification - The company remains classified as an "emerging growth company" and a "smaller reporting company," allowing it to take advantage of reduced disclosure requirements[177][179].