2025-05-13 11:05Financial Performance - The company's revenue for Q1 2025 reached ¥8,047,870, an increase of 50.2% compared to ¥5,359,338 in the same period last year[5] - The net profit attributable to shareholders was -¥94,503, improving from -¥1,908,056 year-on-year[5] - The adjusted operating profit for the reporting period was ¥1,171 million, compared to an adjusted operating loss of ¥937 million in the same period last year[11] - The adjusted net profit for the reporting period was ¥885 million, improving from an adjusted net loss of ¥1,082 million year-on-year[11] - Operating profit for Q1 2025 was CNY 150,673 thousand, compared to a loss of CNY 1,829,645 thousand in Q1 2024[20] - Net profit for Q1 2025 was a loss of CNY 94,503 thousand, significantly improved from a loss of CNY 1,908,056 thousand in Q1 2024[21] Research and Development - R&D expenses totaled ¥3,473,599, representing 43.16% of revenue, a decrease of 18.9 percentage points from 62.10% in the previous year[6] - Research and development expenses for Q1 2025 were CNY 3,473,599 thousand, compared to CNY 3,328,145 thousand in Q1 2024, reflecting a 4.4% increase[20] Cash Flow and Assets - The company reported a net cash flow from operating activities of -¥192,920, an improvement from -¥2,395,729 in the same period last year[5] - Cash flow from operating activities for Q1 2025 was a net outflow of CNY 192,920 thousand, an improvement from a net outflow of CNY 2,395,729 thousand in Q1 2024[23] - The total assets at the end of the reporting period were ¥42,126,494, a decrease of 1.7% from ¥42,834,708 at the end of the previous year[6] - Cash and cash equivalents at the end of Q1 2025 totaled CNY 12,748,136 thousand, down from CNY 14,329,309 thousand at the end of Q1 2024[23] - Total liabilities decreased to CNY 16,920,380 thousand as of March 31, 2025, from CNY 18,659,486 thousand as of December 31, 2024[18] Shareholder Information - The company has issued a total of 1,403,281,823 shares, with 91.80% being issued overseas[12] - Total number of common shareholders at the end of the reporting period was 24,233[13] - The largest shareholder, Amgen, held 246,269,426 shares, representing 17.55% of total shares[13] - Baker Brothers Life Sciences, L.P. and its affiliates held 115,749,859 shares, accounting for 8.25%[13] - HHLR Fund, L.P. and its affiliates owned 92,805,741 shares, which is 6.61% of total shares[13] - Capital Research and Management Company and its affiliates held 83,908,640 shares, representing 5.98%[13] - The top 10 shareholders collectively hold significant stakes, with the largest four shareholders accounting for over 38% of total shares[15] Industry and Future Outlook - The company operates in the biopharmaceutical industry, which is characterized by long R&D cycles and high investment risks[15] - Future business plans and financial performance may significantly differ from expectations due to various uncertainties[15] - The company emphasizes the importance of regulatory approvals and commercial success for its drug candidates[15] Earnings Per Share - The basic and diluted earnings per share were both -¥0.07, an improvement from -¥1.41 year-on-year[5] - The company reported a basic and diluted earnings per share of CNY -0.07 for Q1 2025, an improvement from CNY -1.41 in Q1 2024[21]