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Cogent Biosciences(COGT) - 2025 Q2 - Quarterly Results

Introduction to the Underwriting Agreement This section outlines the proposed issuance and sale of common stock by Cogent Biosciences, Inc. and the roles of the underwriting representatives - Cogent Biosciences, Inc. proposes to issue and sell 22,222,223 shares of common stock ('Firm Shares') and an additional 3,333,333 shares ('Additional Shares') if the Underwriters exercise their option1 - J.P. Morgan Securities LLC, Leerink Partners LLC, and Guggenheim Securities, LLC are acting as representatives for the Underwriters1 - The Company has filed an automatic shelf registration statement on Form S-3 with the SEC, including a prospectus for the securities1 - Key terms like 'Registration Statement,' 'Prospectus,' 'Time of Sale Prospectus,' and 'free writing prospectus' are defined, including documents incorporated by reference23 1. Representations and Warranties The Company provides assurances regarding its legal, financial, and operational status, including SEC filings, corporate authority, and regulatory compliance 1.1. Securities Filings and Disclosure Accuracy The Company represents that its SEC filings, including the Registration Statement, Prospectus, Time of Sale Prospectus, and any free writing prospectuses, comply materially with applicable laws and regulations, are free from material misstatements or omissions, and that the Company is a 'well-known seasoned issuer' Statistical and forward-looking data are also affirmed for reliability and proper disclosure - The Registration Statement is an 'automatic shelf registration statement' and became automatically effective upon filing; no stop order is in effect or threatened4 - Each document incorporated by reference, the Registration Statement, the Prospectus, and the Time of Sale Prospectus, complied or will comply materially with the Securities Act and Exchange Act, and do not contain untrue statements or omissions of material fact562060 - The Company is not an 'ineligible issuer' and is a 'well-known seasoned issuer'; all required free writing prospectuses have been or will be filed and comply materially with the Securities Act7 - All statistical, demographic, and market-related data in the filings are based on reliable and accurate sources Forward-looking statements are included in good faith with a reasonable basis and accompanied by meaningful cautionary statements6466 1.2. Corporate Status and Authority The Company and its subsidiaries are duly incorporated, validly existing, and in good standing, possessing the necessary corporate power and qualifications to conduct their business The Agreement is duly authorized, and all capital stock, including the Shares being offered, is properly authorized, validly issued, fully paid, and non-assessable - The Company is duly incorporated, validly existing, in good standing under Delaware law, and has the corporate power and authority to own its property and conduct its business8 - Each subsidiary is duly incorporated, validly existing, in good standing, and its issued capital stock is duly authorized, validly issued, fully paid, non-assessable, and owned directly by the Company, free and clear of all liens9 - This Agreement has been duly authorized, executed, and delivered by the Company10 - The Shares have been duly authorized and, when issued and delivered, will be validly issued, fully paid, and non-assessable, without being subject to any preemptive or similar rights13 1.3. Compliance with Laws and Regulations The Company asserts its material compliance with a wide array of laws and regulations, including those governing environmental protection, anti-corruption, anti-money laundering, sanctions, healthcare, and data privacy (HIPAA, GDPR) It also confirms that the offering will not contravene any applicable laws or corporate documents - The execution and delivery of the Agreement and the issuance of Shares will not contravene applicable law, the Company's organizational documents, or material agreements, and no governmental consents are required (except Blue Sky laws)14 - The Company and its subsidiaries are in compliance with Environmental Laws, possess all required permits, and have no material environmental liabilities2223 - The Company, its subsidiaries, and affiliates comply with applicable anti-corruption laws and Anti-Money Laundering Laws, and will not use offering proceeds in violation of such laws or Sanctions252729 - The Company and its subsidiaries are in material compliance with all Applicable Laws (including those related to product candidates), possess all material Authorizations, and have conducted preclinical and clinical trials in material compliance with accepted scientific standards and laws3739 - The Company and its subsidiaries are in material compliance with all applicable state and federal data privacy and security laws and regulations, including HIPAA and GDPR, and have implemented commercially reasonable controls for IT Systems and Personal Data676869 1.4. Financial Information and Controls The Company affirms that its consolidated financial statements fairly present its financial position in accordance with GAAP and SEC requirements It also confirms the maintenance of effective internal accounting controls and disclosure controls, and compliance with tax filing and payment obligations - PricewaterhouseCoopers LLP is an independent public accountant as required by the Securities Act and Commission rules47 - The consolidated financial statements present fairly the financial position and results, comply materially with the Securities Act, and are prepared in conformity with GAAP (with exceptions for unaudited interim statements)4850 - The Company and its subsidiaries maintain internal accounting controls sufficient to provide reasonable assurance over financial reporting and asset accountability, with no material weaknesses or changes since the most recent audited fiscal year (except as disclosed)51 - The Company maintains effective disclosure controls and procedures designed to comply with Exchange Act requirements52 - All required federal, state, local, and foreign tax returns have been filed or extended, and all taxes paid (except for good faith contests with GAAP reserves or non-material failures)5556 1.5. Business Operations and Assets The Company represents that it holds good and marketable title to its material personal property and valid leases for real property It also confirms ownership or valid licenses for all material intellectual property, compliance with labor laws, adequate insurance coverage, and possession of necessary regulatory permits for its business operations - The Company does not own real property but has good and marketable title to all material personal property, free and clear of liens (except as described or non-material) Leased real property is held under valid, subsisting, and enforceable leases33 - The Company and its subsidiaries own or have valid licenses for all material Intellectual Property used in their business, and such IP is valid, enforceable, and subsisting (except as disclosed) There are no material infringement claims or challenges to IP rights34 - All patent and patent applications owned or licensed by the Company have been duly filed, prosecuted, and maintained in all material respects36 - No material labor dispute exists or is imminent, and there are no threatened labor disturbances from principal suppliers, manufacturers, or contractors that would have a material adverse effect42 - The Company and its subsidiaries are insured by financially responsible insurers against prudent and customary losses and risks, and possess all necessary regulatory certificates, authorizations, and permits4546 1.6. Other Representations This section includes various other representations, such as the absence of material adverse changes since the Time of Sale Prospectus, no significant pending legal proceedings, no recent stock sales outside of employee plans, no securities ratings, and compliance with Nasdaq listing requirements It also confirms no market manipulation activities and proper disclosure of related-party transactions - There has been no material adverse change or development in the Company's condition, earnings, business, management, prospects, or operations since the Time of Sale Prospectus18 - No material legal or governmental proceedings are pending or threatened against the Company or its subsidiaries (except as described or non-material)19 - Subsequent to the dates of information in the filings, no material liabilities or transactions have occurred, no stock repurchases (except for employee/consultant departures), no non-ordinary dividends, and no material changes in capital stock or debt (except as described)31 - The Company has not sold, issued, or distributed any Common Stock in the six-month period preceding the agreement, other than shares issued pursuant to employee benefit plans or outstanding options/warrants53 - The Shares are listed on the Nasdaq Global Select Market, and the Company is in compliance with all applicable listing requirements57 - The Company has not taken any action designed to stabilize or manipulate the price of the Shares or any reference security, or to violate Regulation M61 2. Agreements to Sell and Purchase This section details the Company's agreement to sell Firm Shares to the Underwriters and the option for Additional Shares - The Company agrees to sell 22,222,223 Firm Shares to the Underwriters at a Purchase Price of $8.46 per share70 - The Underwriters have an option to purchase up to an additional 3,333,333 shares ('Additional Shares') at the Purchase Price71 - The option can be exercised in whole or in part by written notice within 30 days after the agreement date ('Option Period')71 3. Terms of Public Offering This section specifies the initial public offering price per share and the concession offered to dealers - The Shares are to be offered to the public initially at a price of $9.00 per Firm Share73 - A concession not exceeding $0.324 per Firm Share will be offered to certain dealers selected by the Representatives73 4. Payment and Delivery This section outlines the payment schedule and delivery procedures for the Firm Shares and any Additional Shares - Payment for Firm Shares will be made on July 10, 2025 ('Closing Date'), or a designated date not later than July 24, 2025, in immediately available funds74 - Payment for any Additional Shares will be made on the specified 'Option Closing Date,' not later than August 8, 202574 - Shares will be delivered to the Representatives, registered as requested, with transfer taxes paid, against payment of the Purchase Price75 5. Conditions to the Underwriters' Obligations The Underwriters' obligations are contingent upon the accuracy of the Company's representations, the absence of adverse changes, and receipt of legal and financial documentation - The Underwriters' obligations are subject to the accuracy of the Company's representations and warranties as of the agreement date and Closing Date, and the effectiveness of the Registration Statement76 - No stop order suspending the Registration Statement's effectiveness shall be in effect, and no material adverse change in the Company's condition, earnings, business, prospects, or operations shall have occurred since the Time of Sale Prospectus that makes marketing impracticable7778 - The Underwriters must receive various legal opinions and negative assurance letters from Company counsel (Gibson, Dunn & Crutcher LLP, Goodwin Procter LLP) and Underwriters' counsel (Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.)808182 - Receipt of 'comfort letters' from PricewaterhouseCoopers LLP and certificates from the Company's executive officer and CFO confirming representations, compliance, and financial information accuracy is required798688 - Lock-up agreements with certain shareholders, officers, and directors must be in full force and effect87 6. Covenants of the Company The Company commits to various actions, including SEC filing updates, expense payments, and restrictions on stock sales during a lock-up period - The Company covenants to furnish copies of all SEC filings and amendments to the Representatives, and to promptly advise them of any significant developments related to the Registration Statement or Prospectus919299 - The Company will prepare and furnish amendments or supplements to the Time of Sale Prospectus or Prospectus if necessary to prevent misleading statements or ensure compliance with applicable law9596 - The Company agrees to pay all expenses incident to the performance of its obligations under the Agreement, including legal, accounting, printing, transfer, listing, and road show costs (with specific limits for Underwriters' counsel fees)102103 - During a 60-day 'Restricted Period' after the Prospectus date, the Company will not offer, sell, or transfer Common Stock or convertible securities, or file related registration statements, without the Representatives' prior written consent106 - Exceptions to the lock-up include sales under the agreement, exercise of existing options/warrants, S-8 filings, sales under existing 'at the market' programs (with conditions), and issuances for M&A or strategic transactions (up to 5% of outstanding shares, with lock-up for recipients)107 7. Covenants of the Underwriters Each Underwriter agrees not to take actions that would necessitate additional free writing prospectus filings by the Company - Each Underwriter covenants not to take any action that would require the Company to file a free writing prospectus under Rule 433(d) that would otherwise not be required108 8. Indemnity and Contribution This section establishes mutual indemnification obligations between the Company and Underwriters for offering document liabilities, with provisions for contribution - The Company agrees to indemnify the Underwriters (and their controlling persons, affiliates, directors, officers) against losses arising from untrue statements or omissions of material fact in the offering documents, except for information furnished by the Underwriters109 - Each Underwriter severally agrees to indemnify the Company (and its directors, officers, controlling persons) for losses arising from untrue statements or omissions based on information specifically furnished by that Underwriter for use in the offering documents110 - Procedures for notification, retention of counsel, payment of legal fees, and settlement of proceedings are outlined111 - If indemnification is unavailable or insufficient, parties will contribute to losses based on relative benefits received from the offering or relative fault, considering factors like intent, knowledge, and opportunity to correct112113 - The Underwriters' contribution obligations are several, not joint, and capped at the public offering price of the shares underwritten by them These provisions survive the termination of the agreement and any investigations113114115 9. Termination The Underwriters may terminate the agreement under specific adverse market, trading, or geopolitical conditions prior to the Closing Date - The Underwriters may terminate the Agreement if, prior to the Closing Date, certain adverse events occur, including: (i) suspension or material limitation of trading on major exchanges, (ii) suspension of Company securities trading, (iii) material disruption in securities settlement services, (iv) a moratorium on commercial banking activities, or (v) any outbreak of hostilities, change in financial markets, or calamity/crisis making the offering impracticable or inadvisable116 10. Effectiveness; Defaulting Underwriters The agreement becomes effective upon execution, with provisions for handling defaulting Underwriters and Company reimbursement for termination due to non-compliance - The Agreement becomes effective upon execution and delivery by the parties118 - If defaulting Underwriters fail to purchase shares, non-defaulting Underwriters may be obligated to purchase their proportional share if the default is not more than one-tenth of the total shares119 - If the default exceeds one-tenth and no satisfactory arrangements are made within 36 hours, the Agreement may terminate without liability for non-defaulting Underwriters or the Company119 - The Company will reimburse Underwriters for out-of-pocket expenses if the Agreement is terminated due to the Company's non-compliance or inability to perform its obligations120 11. Entire Agreement This agreement constitutes the complete understanding between the Company and Underwriters, clarifying their arm's-length relationship and absence of fiduciary duties - This Agreement, along with any contemporaneous and prior written agreements related to the offering, constitutes the entire agreement between the Company and the Underwriters122 - The Company acknowledges that the Underwriters act at arm's length, are not agents, owe no fiduciary duties, and are not providing legal, tax, investment, accounting, or regulatory advice123 - The Company waives any claims against the Underwriters arising from an alleged breach of fiduciary duty123 12. Counterparts The agreement may be executed in multiple counterparts, with electronic delivery and signatures deemed valid - The Agreement may be signed in two or more counterparts, each considered an original124 - Delivery of executed counterparts by facsimile or electronic mail (including electronic signatures) is deemed duly and validly delivered124 13. Applicable Law The agreement and related disputes are governed by the internal laws of the State of New York - This Agreement and any related claims or disputes shall be governed by and construed in accordance with the internal laws of the State of New York125 14. Waiver of Jury Trial All parties irrevocably waive their right to a jury trial for any disputes arising from this agreement - Each of the parties irrevocably waives any right to trial by jury in any suit or proceeding arising out of or relating to this Agreement125 15. Consent to Jurisdiction The parties agree to the exclusive jurisdiction of federal and New York State courts in Manhattan for any legal proceedings - Any legal suit, action, or proceeding arising from the Agreement shall be instituted in the federal courts of the United States or the courts of the State of New York located in the City and County of New York, Borough of Manhattan126 - The parties irrevocably submit to the exclusive jurisdiction of these courts and waive any objection to venue or inconvenient forum126 16. Headings Section headings are for reference only and do not form part of the agreement's substantive content - The headings of the sections of this Agreement are for convenience of reference only and shall not be deemed a part of this Agreement128 17. Persons Entitled to Benefit of Agreement The agreement benefits the parties and their successors, but no other persons, including share purchasers, have rights under it - This Agreement shall inure to the benefit of and be binding upon the parties, their respective successors, and the officers, directors, controlling persons, and affiliates referred to herein129 - No other person, including purchasers of Shares from any Underwriter, is intended to have any legal or equitable right, remedy, or claim under this Agreement129 18. Survival Indemnities, contribution rights, representations, warranties, and agreements survive the delivery and payment for shares, remaining in effect despite termination or investigation - The respective indemnities, rights of contribution, representations, warranties, and agreements of the Company and the Underwriters shall survive the delivery of and payment for the Shares130 - These provisions shall remain in full force and effect regardless of any termination of this Agreement or any investigation130 19. Compliance with USA Patriot Act Underwriters are required to obtain and verify client identification information in accordance with the USA Patriot Act - In accordance with the USA Patriot Act, the Underwriters are required to obtain, verify, and record information that identifies their respective clients, including the Company131 20. Notices All communications under the agreement must be in writing and are effective upon receipt, with specific contact details provided - All communications under the Agreement must be in writing and are effective only upon receipt132 - Specific contact information, including addresses and attention lines, is provided for notices to the Underwriters (J.P. Morgan, Leerink, Guggenheim) and the Company (Cogent Biosciences, Inc.)132 21. Recognition of the U.S. Special Resolution Regimes This section addresses the applicability of U.S. Special Resolution Regimes to Underwriters, limiting default rights under such regimes - If an Underwriter (defined as a 'Covered Entity') becomes subject to a U.S. Special Resolution Regime, the transfer of this Agreement and any related interests/obligations will be effective as if governed by U.S. law134 - Default Rights against a Covered Entity Underwriter or its BHC Act Affiliate are limited to the extent exercisable under the U.S. Special Resolution Regime135 - Definitions for 'BHC Act Affiliate,' 'Covered Entity,' 'Default Right,' and 'U.S. Special Resolution Regime' are provided136 Signatures This section contains the formal execution and acceptance of the Underwriting Agreement by the Company and the Underwriters - The Agreement is signed by John Green, Chief Financial Officer of Cogent Biosciences, Inc.138 - The Agreement is accepted by Benjamin Burdett (J.P. Morgan Securities LLC), Jon Civitarese (Leerink Partners LLC), and Shiv Taylor (Guggenheim Securities, LLC) on behalf of themselves and the several Underwriters138 Schedule I: Underwriters and Firm Shares This schedule details the specific allocation of Firm Shares to be purchased by each Underwriter Number of Firm Shares To Be Purchased by Each Underwriter | Underwriter | Number of Firm Shares | | :---------- | :-------------------- | | J.P. Morgan Securities LLC | 9,777,778 | | Leerink Partners LLC | 6,666,667 | | Guggenheim Securities, LLC | 4,444,445 | | LifeSci Capital LLC | 1,333,333 | | Total | 22,222,223 | Schedule II: Time of Sale Prospectus Information This schedule provides key offering parameters, including the preliminary prospectus date, public price, and share counts - The preliminary prospectus is dated July 8, 2025142 - The price per Share to the public is $9.00142 - The number of Firm Shares offered is 22,222,223142 - The Underwriters' option to purchase Additional Shares is 3,333,333142 Exhibit A: Form of Lock-Up Letter This exhibit presents the form of the lock-up agreement restricting insiders from selling shares for a specified period post-offering - The lock-up letter is intended to induce the Underwriters to continue their efforts in connection with the Public Offering144 - During a 'Restricted Period' of 60 days after the final prospectus supplement date, the undersigned agrees not to offer, sell, or transfer Common Stock or related securities, or enter into swaps that transfer economic consequences of ownership, without the Representatives' prior written consent144 - Key exceptions to the lock-up include shares acquired in the Public Offering or open market, bona fide gifts, distributions to affiliates/family (with donee lock-up), transfers by will, exercise of existing options/warrants (underlying stock remains locked up), transfers by operation of law, repurchases by the Company upon employment termination, establishment of Rule 10b5-1 plans (no transfers during Restricted Period), cashless exercises for tax withholding, and transfers in connection with a Board-approved Change of Control transaction145146147 - The undersigned also agrees not to demand or exercise any registration rights during the Restricted Period and consents to stop transfer instructions148 - The lock-up agreement is irrevocable and binding, but automatically terminates under specific conditions, such as the Public Offering not proceeding or the Underwriting Agreement not being executed by July 31, 2025149150