Jazz Pharmaceuticals(JAZZ) - 2025 Q3 - Quarterly Results

Financial Performance - Total revenues for Q3 2025 increased by 7% year-over-year to $1,126.1 million, compared to $1,055.0 million in Q3 2024[12] - Net product sales rose by 11% to $431.4 million in Q3 2025, driven by strong growth from Epidiolex and Xywav[6] - Modeyso achieved sales of $11.0 million in its first quarter post-launch, following FDA accelerated approval[6] - The company narrowed its 2025 total revenue guidance to a range of $4.175 billion to $4.275 billion[6] - Total revenues for the three months ended September 30, 2025, increased to $1,126,107, up 6.7% from $1,054,969 in the same period of 2024[36] - Product sales, net for the nine months ended September 30, 2025, reached $2,889,401, a 3.4% increase compared to $2,795,953 in 2024[36] Income and Expenses - GAAP net income for Q3 2025 was $251.4 million, compared to $215.1 million in Q3 2024[9] - Non-GAAP adjusted net income increased to $500.7 million in Q3 2025 from $412.4 million in Q3 2024[9] - Operating expenses for the three months ended September 30, 2025, totaled $1,068,598, a significant increase from $794,759 in 2024, reflecting a rise of 34.5%[36] - SG&A expenses rose to $1,786 - $1,846 million in Q3 2025, influenced by litigation settlements totaling $151.5 million and increased compensation-related expenses[19] - R&D expenses decreased to $771 - $810 million in Q3 2025, mainly due to lower clinical study costs related to certain programs, partially offset by costs from the Chimerix acquisition[19] Cash and Assets - Cash, cash equivalents, and investments totaled $2.0 billion as of September 30, 2025, with long-term debt at $5.4 billion[16] - Cash and cash equivalents decreased to $1,326,070 as of September 30, 2025, down from $2,412,864 at the end of 2024[38] - Total assets as of September 30, 2025, were $11,356,485, a decrease from $12,012,257 at the end of 2024[38] Tax and Loss Projections - The company recognized an income tax benefit of $205.9 million in Q3 2025 from deferred tax assets acquired through the Chimerix acquisition[17] - The effective tax rate for 2025 is expected to be between 35% - 45% on a GAAP basis, while the non-GAAP adjusted effective tax rate is projected at (20)% - (15)%[19][22] - Projected net loss for 2025 is estimated at $(435) - $(315) million, with a net loss per diluted share of $(7.10) - $(5.20)[19] - The company reported a net loss of $(559,599) for the nine months ended September 30, 2025, compared to a net income of $369,005 in 2024[36] Research and Development - The company announced a global licensing agreement with Saniona to develop SAN2355 for epilepsy and other indications[8] - Jazz Pharmaceuticals is focused on expanding its pipeline and advancing clinical trials, including the ongoing Phase 3 ACTION trial for Modeyso[31] - Acquired in-process research and development (IPR&D) expenses are projected at $948 million for 2025, reflecting the upfront payment for a global license agreement with Saniona[19] Earnings Per Share - The diluted earnings per share for the three months ended September 30, 2025, was $4.08, compared to $3.42 in the same period of 2024, reflecting a 19.3% increase[42] - Non-GAAP adjusted net income is projected to be between $475 million and $525 million, with a diluted EPS of $7.65 to $8.45[55]