Financial Performance - The Company reported no revenue for the year ended December 31, 2025, a decrease of 100% compared to $500,000 in 2024[150]. - Exicure, Inc. reported total revenue of $0 for the year ended December 31, 2025, compared to $500,000 in 2024, indicating a 100% decrease in revenue[221]. - The net loss for 2025 was $4.946 million, a 49% improvement from a net loss of $9.701 million in 2024[163]. - Exicure, Inc. incurred a net loss of $4,946,000 in 2025, compared to a net loss of $9,701,000 in 2024, reflecting a 48.9% improvement in net loss[221]. - The accumulated deficit increased to $(204,210,000) in 2025 from $(199,264,000) in 2024, indicating a growing financial challenge[219]. - The company has an accumulated deficit of $223.0 million, with net losses of $4.9 million and $9.7 million for the years ended December 31, 2025 and 2024, respectively[65]. - The company's total operating expenses for 2025 were $4,233,000, a significant reduction from $12,732,000 in 2024, representing a 66.7% decrease[221]. - Total operating expenses decreased by 67% to $4.233 million in 2025, down from $12.732 million in 2024[163]. - General and administrative expenses increased by 25% to $6.831 million in 2025, up from $5.449 million in 2024[163]. - Research and development expenses for 2025 amounted to $3.286 million, a 100% increase from zero in 2024[163]. Cash and Financing - As of December 31, 2025, the company's cash and cash equivalents were approximately $3.7 million[53]. - The Company had approximately $3.7 million in cash and cash equivalents as of December 31, 2025, raising concerns about its ability to fund operations for the next 12 months[132]. - The company's cash, cash equivalents, and restricted cash decreased to $3,746,000 in 2025 from $12,508,000 in 2024, a decline of 70%[219]. - The Company expects to seek financing through equity offerings, but faces challenges due to its current condition and uncertainty over future direction[133]. - The company is exploring strategic alternatives, including private company acquisitions and raising additional capital[29]. - The company is exploring strategic alternatives and may need to seek bankruptcy protection if additional financing is not secured[180]. - The company has no current source of revenue and is dependent on obtaining substantial additional financing to support operations[53]. - The company may face challenges in raising additional capital through equity offerings or debt financings, which could lead to dilution for existing stockholders[86]. Operational Challenges - The company faces substantial doubt about its ability to continue as a going concern, requiring additional funding in the near term to support operations[60]. - The company has experienced significant turnover in its board and senior management, which may create uncertainty regarding its strategic direction and business priorities[58]. - The company has a significant working capital deficiency and has incurred substantial losses, raising doubts about its ability to continue as a going concern[213]. - The company received a payment demand letter for approximately $0.7 million in unpaid rent, which could impact its operational capabilities[73]. - The company has identified material weaknesses in its internal controls over financial reporting, which could lead to inaccuracies in financial statements[75]. - The company identified material weaknesses in its internal control over financial reporting, leading to the restatement of its unaudited interim condensed consolidated financial statements for Q1 and Q2 2023[78]. - The company incurred unanticipated costs for accounting and legal fees related to the restatement, which may continue to affect its financial condition and reputation[78]. Stock and Ownership - HiTron beneficially owns approximately 25% of the outstanding shares of common stock, significantly influencing the company, while CBI USA and DGP collectively own about 10%[80]. - The company has experienced an "ownership change" as defined by Section 382(g) during Q4 2022, which restricts its ability to use net operating loss carryforwards to offset taxable income[91]. - As of December 31, 2023, the company ceased operations of its historical business enterprise, resulting in a zero limitation on the use of historical net operating losses prior to the ownership change[94]. - The market price of the company's common stock has been highly volatile, influenced by various factors including the influence of significant stockholders and general market conditions[84]. - The company's common stock was approved for listing on the Nasdaq Capital Market under the symbol "XCUR" and began trading on July 31, 2019, with a last reported sale price of $4.54 per share on March 17, 2026[115]. - As of March 17, 2026, the company had 6,373,915 shares of common stock outstanding held by 88 stockholders of record[116]. - The company has never declared or paid cash dividends on its common stock and does not intend to do so for the foreseeable future[117]. Regulatory and Compliance Issues - The company has received multiple deficiency notices from Nasdaq regarding compliance with listing requirements, raising the risk of delisting[61]. - The Company has received deficiency notices from Nasdaq regarding compliance with listing requirements, but regained compliance by filing its Form 10-Q on June 27, 2025[137][138]. - Compliance with European data protection laws, including GDPR, is critical, as failure to comply may materially adversely affect the company's business and financial condition[79]. - The company is subject to risks related to government regulation, which could impact its operations and financial results[79]. - FINRA sales practice requirements may limit stockholders' ability to buy and sell the company's stock due to its low stock price, potentially affecting market activity[95].
Exicure(XCUR) - 2025 Q4 - Annual Report