Financial Performance - The net loss for the three months ended March 31, 2022, was $24.3 million, compared to a net loss of $18.7 million for the same period in 2021, representing an increase of $5.6 million[68]. - The total operating expenses for the three months ended March 31, 2022, were $24.3 million, compared to $18.8 million for the same period in 2021, reflecting an increase of $5.5 million[82]. - The company recorded a consolidated net loss of $24.3 million for the three months ended March 31, 2022[94]. - The company anticipates continuing to incur net losses for the foreseeable future, with expectations to fund operations into the second half of 2024 based on current cash levels[90]. Research and Development - Research and development expenses for the three months ended March 31, 2022, were $16.9 million, an increase of $6.5 million from $10.4 million in the same period in 2021[82]. - The ongoing clinical development of mecbotamab vedotin and ozuriftamab vedotin is expected to increase expenses and capital requirements substantially[69]. - Research and development expenses increased to $16.9 million for the three months ended March 31, 2022, up from $10.4 million in the same period of 2021, representing a $6.5 million increase[84]. Cash and Liquidity - Cash and cash equivalents as of March 31, 2022, totaled approximately $219.4 million, expected to fund operations into the second half of 2024[72]. - As of March 31, 2022, the company had cash and cash equivalents of $219.4 million, down from $245.0 million at the end of 2021[100]. - Net cash used in operating activities was $25.1 million for the three months ended March 31, 2022, compared to $15.0 million in the same period of 2021, indicating a significant increase in cash outflow[94][95]. - Future funding requirements will depend on various factors, including the progress of clinical trials and the costs associated with manufacturing and commercialization[89]. Operating Expenses - Total external expenses rose to $12.4 million in Q1 2022, compared to $7.6 million in Q1 2021, marking an increase of $4.8 million[84]. - General and administrative expenses decreased to $7.4 million in Q1 2022 from $8.4 million in Q1 2021, a reduction of $1.0 million[85]. - The company has incurred significant losses and will require substantial additional capital to develop product candidates and fund operations[70]. Revenue Expectations - The company does not expect to generate meaningful revenue from product sales for the foreseeable future and anticipates continued significant operating expenses[68]. - The company has not generated any revenue from product sales to date and does not expect to do so in the near future[74]. Impact of COVID-19 - The impact of COVID-19 has caused modest delays in clinical trials, but overall timelines for study completion have not changed significantly[73]. Interest Income - Interest income decreased to $85,000 in Q1 2022 from $98,000 in Q1 2021, reflecting lower average cash balances[86]. Off-Balance Sheet Arrangements - The company has not entered into any off-balance sheet arrangements as defined by SEC regulations[99].
BioAtla(BCAB) - 2022 Q1 - Quarterly Report