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悦康药业(688658) - 2022 Q4 - 年度财报

Financial Performance - The proposed cash dividend for 2022 is RMB 11.00 per 10 shares, totaling RMB 494.5 million based on a total share capital of 450 million shares[6]. - The net profit attributable to shareholders for 2022 is RMB 335.0147 million, with a cash dividend payout ratio of 147.75%[6]. - The company's operating revenue for 2022 was CNY 4,541,945,402.40, a decrease of 8.53% compared to CNY 4,965,725,984.69 in 2021[23]. - The net profit attributable to shareholders for 2022 was CNY 335,014,720.83, down 38.57% from CNY 545,316,048.79 in 2021[23]. - The net cash flow from operating activities was negative CNY 121,168,954.78, a decline of 123.52% compared to CNY 515,238,540.75 in 2021[23]. - The basic earnings per share for 2022 were CNY 0.74, a decrease of 38.84% from CNY 1.21 in 2021[24]. - The total revenue for 2022 was 4,541,945,402.40 RMB, with a net profit of 373,529,813.99 RMB before accounting for share-based payments[33]. - The company reported a 31.30% year-on-year decrease in net profit after excluding the impact of share-based payments[32]. - The company achieved a total R&D investment of CNY 451.84 million in 2022, representing a 73.25% increase compared to the previous year[71]. Operational Risks and Governance - The company has detailed various operational risks and corresponding mitigation measures in the report[4]. - The company has received a standard unqualified audit report from the accounting firm Rongcheng[5]. - There are no significant non-operating fund occupations by controlling shareholders or related parties[8]. - The company has not violated decision-making procedures for external guarantees[8]. - The company has not faced any issues with a majority of directors being unable to ensure the authenticity and completeness of the annual report[8]. - The company has not reported any special arrangements for corporate governance[8]. - The report includes a forward-looking statement risk disclaimer, indicating that future plans and strategies do not constitute a commitment to investors[7]. Research and Development - The R&D expenditure as a percentage of operating revenue increased to 9.95% in 2022, up 4.70 percentage points from 5.25% in 2021[24]. - The company is focusing on the development of innovative drugs and improving existing formulations to enhance clinical advantages[16]. - The company has established 9 core R&D platforms and has a total of 54 ongoing R&D projects, including 16 innovative drugs and 38 generic drugs[38]. - The company has received a total of 205 patents, with 79 new patents applied for in 2022, including 48 invention patents[38]. - The company has a strong R&D focus in areas such as cardiovascular, digestive systems, diabetes, reproductive systems, oncology, and anticoagulation, with a rich pipeline of products[145]. - The company is currently conducting clinical trials for multiple projects, including YKYY009, which targets the Omicron variant of the coronavirus[75]. - The company has ongoing projects in the development of mRNA vaccines and nucleic acid drugs, with significant progress reported in clinical phases[75]. - The company has made significant advancements in peptide drug development, establishing a comprehensive research system that integrates drug discovery and clinical development[65]. Market and Competitive Position - The pharmaceutical manufacturing industry in China experienced a revenue decline of 1.6% in 2022, totaling CNY 2,911.14 billion, with a profit drop of 31.8% to CNY 428.87 billion[54]. - The company has been recognized among the top 100 pharmaceutical manufacturers in China, reflecting its strong market position and operational capabilities[56]. - The company is recognized as a leading entity in the nucleic acid and peptide drug development sectors, being one of the few firms with capabilities in mRNA vaccines, small nucleic acid drugs, and peptide drugs[57]. - The company has a diverse product portfolio covering cardiovascular, digestive, anti-infection, endocrine, oncology, and reproductive health medications[56]. - The company is committed to international expansion, increasing the proportion of overseas sales revenue, and enhancing production processes to meet international standards[156]. Financial Management and Investments - The company has a comprehensive quality management system in place, adhering to GMP standards, ensuring product safety and quality throughout the manufacturing process[47]. - The company has a robust process development and scale-up platform that meets international quality requirements for GMP production of candidate small nucleic acids and mRNA vaccines[65]. - The company has established a technology platform for high-end pharmaceutical excipients, producing unique products with significant performance and cost advantages[66]. - The company has received approval for new drug development projects, including a contraceptive drug with therapeutic effects, which was approved in April 2022[69]. - The company plans to continue expanding its mRNA nucleic acid drug platform, which has led to significant investment in R&D[106]. Human Resources and Management - The company has 537 R&D personnel, an increase from 347 in the previous period, representing 16.84% of the total workforce, up from 12.24%[79]. - The total pre-tax remuneration for the reporting period amounted to 1,321.46 million CNY[177]. - The company has a strong leadership team with extensive experience in the pharmaceutical industry, including roles in various associations and organizations[178]. - The company has established a talent development mechanism and is increasing the recruitment of outstanding talents to build an innovative and efficient team, ensuring human resource support for strategic goals[165]. - The company has implemented a comprehensive training plan to enhance employee skills and support business objectives[198]. Compliance and Regulatory Environment - The company has not faced any penalties from securities regulatory authorities in the past three years, indicating compliance with regulations[186]. - The company operates in a macroeconomic environment that is currently experiencing cyclical fluctuations, which could adversely affect its operating performance and profitability[101]. - The company is subject to risks from regulatory changes regarding key monitored drug lists, which could restrict sales of certain products[97]. - The company has established a compliance management system, but risks remain regarding improper commercial behavior by downstream clients or employees[92].