Financial Performance - As of March 31, 2023, Nautilus Biotechnology reported total assets of $345.9 million, a decrease from $350.1 million as of December 31, 2022[20]. - The company incurred a net loss of $14.97 million for the three months ended March 31, 2023, compared to a net loss of $15.76 million for the same period in 2022, representing a 5% improvement[22]. - Total operating expenses for Q1 2023 were $18.06 million, up from $16.02 million in Q1 2022, reflecting a 12.7% increase[22]. - Cash and cash equivalents decreased to $88.5 million as of March 31, 2023, down from $114.5 million at the end of 2022, indicating a cash decrease of 22.8%[20]. - The company reported interest income of $3.1 million for Q1 2023, significantly higher than $0.26 million in Q1 2022, marking an increase of over 1,100%[22]. - Nautilus Biotechnology's accumulated deficit increased to $153.5 million as of March 31, 2023, compared to $138.6 million at the end of 2022[20]. - The company had total stockholders' equity of $303.7 million as of March 31, 2023, down from $314.9 million at the end of 2022, a decrease of 3.5%[20]. - Cash used in operating activities for Q1 2023 was $12.52 million, compared to $12.34 million in Q1 2022, indicating a slight increase in cash outflow[29]. - The company expects to continue incurring net operating losses and negative cash flows from operations for the foreseeable future[34]. - The company raised approximately $345.5 million from PIPE investors and the business combination, with transaction costs of about $18.2 million[35]. - As of March 31, 2023, the company had cash, cash equivalents, and short-term investments totaling $167.3 million, which is expected to fund operations for the next twelve months[35]. - The company may need to seek additional equity or debt financing if capital resources are exhausted sooner than expected[35]. - The company has not experienced any losses related to credit risk on cash or investments, indicating a stable financial position[39]. - The company recorded depreciation expense of $400,000 for the three months ended March 31, 2023, compared to $300,000 for the same period in 2022, indicating a year-over-year increase of 33.3%[59]. - The company had 124,866,392 shares issued and outstanding as of March 31, 2023[63]. - The company incurred a net loss of $15.0 million for the three months ended March 31, 2023, driven by operating losses and changes in assets and liabilities[128]. - The company reported a net increase in cash, cash equivalents, and restricted cash of $(26.0) million for the three months ended March 31, 2023[127]. Operational Challenges - The company relies on single-source suppliers for certain components, which poses a risk if these suppliers are lost[40]. - The company is subject to risks typical of pre-clinical stage biopharmaceutical companies, including dependence on key individuals and the need for additional financing[41]. - The COVID-19 pandemic has caused volatility in financial markets, which may affect the company's future access to capital[36]. - The company has not generated any revenue since its inception and relies on successful development and commercialization of its Nautilus platform for future revenue[96]. - The company is dependent on third parties for certain aspects of the development and commercialization of its proteomics platform, which remains in the development stage[154]. - The company may need to raise additional capital to fund its development and commercialization plans, which could impose additional operational restrictions[155]. - The company has experienced difficulties with co-development partners in delivering component technologies on time, which could impact development timelines[168]. - The company faces challenges in manufacturing its products at commercial scale, which could delay the commercialization of the Nautilus platform and result in lost revenue[181]. - The commercialization of the Nautilus platform is subject to numerous risks, including potential delays in product development and regulatory approvals[176]. - The company faces risks related to third-party collaborations for technology development, which could affect timelines and costs[195]. Future Prospects - The company plans to commercialize its proteomics platform in three phases, with meaningful early access engagements and associated revenue expected to begin at the start of 2024[99]. - Nautilus Biotechnology is currently in the collaboration phase with biopharmaceutical companies to validate the performance of its products, with a broader commercial launch anticipated in mid-2024[99]. - The company expects to invest significantly in sales, marketing, and distribution capabilities to achieve substantial revenue growth and profitability[183]. - The Nautilus platform's market acceptance will depend on its ability to demonstrate reliable performance and justify its anticipated costs compared to alternative products[180]. - Future funding requirements will depend on various factors, including the pace of development and potential changes in business strategy[106][124]. - The company anticipates meaningful early access engagements and associated revenue to begin at the start of 2024, leading into a broader commercial launch in mid-2024[170]. - Revenue is expected to primarily come from biotechnology companies and life science laboratories, with potential fluctuations due to customer spending policies[196]. Financial Risks - The company may face dilution of stockholder equity if additional funds are raised through equity securities[126]. - The company believes its current cash resources will be sufficient for at least 12 months, but may need to raise additional capital if liquidity requirements are not met[207]. - Potential risks associated with raising funds include dilution of stockholder equity and unfavorable terms if debt securities are issued[209]. - The company may face challenges in obtaining financing due to adverse global economic conditions and disruptions in financial markets[210]. - Investor concerns regarding the financial system could lead to less favorable financing terms, impacting the company's ability to acquire necessary funding[214]. - The financial stability of the company could be adversely affected by liquidity constraints or failures in the financial services industry[211]. Market Competition - Competition in the life sciences technology market is significant, with established companies holding competitive advantages[190]. - The company must continuously innovate to maintain market relevance and attract new customers[192]. - The Nautilus platform's market size may be smaller than estimated, impacting sales potential[185]. - The successful introduction of the Nautilus platform will require substantial engagement with the scientific community to encourage acceptance and validate its utility[179]. - The company relies on intellectual property protection to maintain a competitive edge, but faces risks related to the adequacy and enforcement of such protections[215]. - The patent application process is complex and costly, with uncertainties regarding the issuance and enforceability of patents[217].
Nautilus Biotechnology(NAUT) - 2023 Q1 - Quarterly Report