Illumina(ILMN) - 2025 Q1 - Quarterly Report

Revenue Performance - Revenue decreased 1% in Q1 2024 to $1,076 million compared to $1,087 million in Q1 2023, primarily due to a decrease in sequencing instruments revenue [134]. - Core Illumina total product revenue decreased by $47 million, or 5%, in Q1 2024, primarily due to a $44 million decrease in sequencing instruments revenue [138]. - Total revenue for Q1 2024 was $1,076 million, a decrease of 1.0% compared to $1,087 million in Q1 2023 [21]. - Product revenue decreased to $876 million, down 5.0% from $922 million in the same period last year [21]. - Service and other revenue increased to $200 million, up 21.2% from $165 million in Q1 2023 [21]. - The company generated $979 million in revenue from the Americas, down from $1,076 million in Q1 2023, while revenue from Europe increased to $279 million from $261 million [47]. Profitability and Margins - Gross margin increased to 62.0% in Q1 2024 from 60.3% in Q1 2023, driven by a favorable mix of sequencing consumables and operational cost savings [134]. - Gross profit for Q1 2024 was $667 million, compared to $655 million in Q1 2023, reflecting a gross margin improvement [21]. - Loss from operations was $(111) million in Q1 2024, an increase from $(64) million in Q1 2023, due to a $59 million increase in operating expenses [134]. - Operating expenses rose to $778 million, an increase of 8.2% from $719 million in Q1 2023 [21]. - Total operating expenses as a percentage of revenue increased to 72.3% in Q1 2024 from 66.1% in Q1 2023 [136]. - The net loss for Q1 2024 was $126 million, a significant decline from a net income of $3 million in Q1 2023, representing a 4,300% decrease [149]. Cash and Investments - Cash, cash equivalents, and short-term investments totaled $1,115 million at the end of Q1 2024, with approximately $614 million held by foreign subsidiaries [135]. - Cash and cash equivalents increased by $60 million from December 31, 2023, totaling approximately $1,108 million as of March 31, 2024 [153]. - Net cash provided by operating activities in Q1 2024 was $77 million, up from $10 million in Q1 2023 [165]. - The company invested $36 million in capital expenditures and $12 million in strategic investments during Q1 2024 [167]. Regulatory and Legal Matters - The divestiture of GRAIL is expected to be executed by the end of Q2 2024, following the European Commission's approval of the divestment plan [130]. - The company is subject to ongoing legal and regulatory proceedings regarding the acquisition of GRAIL, which may result in significant financial penalties and operational restrictions [176]. - The FTC issued an order requiring the company to divest GRAIL, reversing a previous ruling in favor of the company [177]. - The company is currently facing regulatory challenges regarding the acquisition of GRAIL, including a prohibition decision from the European Commission and a divestiture requirement [11]. - The European Commission imposed a fine of approximately €432 million, representing the maximum fine of 10% of the company's consolidated annual revenues for fiscal year 2022 [186]. - The company filed an appeal against the European Commission's Prohibition Decision on November 17, 2022, which found the acquisition incompatible with the internal market in Europe [98]. Taxation - The effective tax rate was (15.3)% in Q1 2024 compared to 103.9% in Q1 2023, primarily due to the impact of research and development expense capitalization [134]. - Effective tax rate in Q1 2024 was (15.3)%, compared to 103.9% in Q1 2023, influenced by $21 million tax expense from capitalizing R&D expenses and $18 million from GRAIL pre-acquisition losses [149]. Future Outlook and Strategic Initiatives - The company anticipates sufficient funds to meet near-term capital and operating needs for at least the next 12 months [162]. - The company is focused on implementing cost reduction plans, which may incur higher costs than anticipated [11]. - Management's outlook includes expectations for growth and market position, contingent on successful product development and regulatory navigation [12]. - Macroeconomic factors such as inflation and supply chain pressures are expected to continue impacting sales and operations in 2024 [133].