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HLN vs. LMAT: Which Stock Should Value Investors Buy Now?
HLNHaleon plc(HLN) ZACKS·2024-07-16 16:46

Core Viewpoint - Acadia Pharmaceuticals is focused on developing innovative treatments for central nervous system disorders and rare diseases, with a commercial portfolio that includes Nuplazid and Daybue, and is actively expanding its pipeline to reduce dependency on Nuplazid sales [1][6]. Financial Performance - In Q1 2024, Nuplazid sales rose by 10% year over year to 129.9million,attributedtoincreasednewpatientstartsandhigherpricingbenefits[2].Daybue,launchedinApril2023,generatednetproductsalesof129.9 million, attributed to increased new patient starts and higher pricing benefits [2]. - Daybue, launched in April 2023, generated net product sales of 75.9 million in its third full quarter, contributing to incremental revenues for the company [8][17]. Product Development and Pipeline - Acadia has expanded its licensing agreement with Neuren, acquiring rights to market trofinetide outside North America and exclusive global rights to NNZ-2591 for Rett syndrome and Fragile X syndrome [3]. - The company initiated a phase III COMPASS study for carbetocin nasal spray (ACP-101) targeting hyperphagia in Prader-Willi syndrome, with plans to submit a new drug application if successful [5][20]. - Acadia is also developing ACP-204 for Alzheimer's disease psychosis, having started a mid-stage study to evaluate its safety and efficacy [11]. Legal and Competitive Landscape - In late 2023, favorable court rulings in Delaware reinforced Acadia's patent for Nuplazid, which is expected to preserve its sales growth potential due to the lack of generic alternatives [4][19]. - Acadia faces competition from other companies, such as Axsome Therapeutics, which has a portfolio of CNS product candidates and has received FDA approval for its product Auvelity [22]. Market Position and Stock Performance - Acadia's stock has seen a decline of 42.4% year to date, contrasting with a 2.7% decline in the industry [18]. - The company currently holds a Zacks Rank 2 (Buy), indicating a favorable outlook compared to other stocks in the drug/biotech industry [13][23].