PainReform Ltd. Confirms Sutures Compatibility in Human Clinical Trials for PRF-110

Core Insights - PainReform Ltd. announced positive findings regarding the compatibility of its lead product PRF-110 with surgical sutures in human clinical trials, indicating its potential for extended, non-opiate post-surgical pain relief [1][4] Group 1: Product and Clinical Trials - PRF-110 is designed to provide extended post-surgical pain relief without the use of opiates, utilizing a proprietary extended-release drug-delivery system [5] - Comprehensive in vitro studies were conducted to assess the impact of PRF-110 on both nonabsorbable (PROLENE™) and resorbable (Vicryl™) sutures, focusing on mechanical properties such as breaking force and elongation [2] - Results showed that PRF-110 does not affect the mechanical properties of either type of suture, suggesting compatibility with surgical conditions [3] Group 2: Company Leadership and Future Directions - Ehud Geller, Chairman and interim CEO, emphasized the importance of these findings as a milestone for the safety and efficacy of PRF-110, advancing the product toward commercialization [4] - The ability to provide extended pain relief without compromising suture integrity is highlighted as a significant advancement in post-surgical care [4]