Core Insights - Aclaris Therapeutics entered into an exclusive license agreement with Biosion Inc for worldwide rights (excluding Greater China) to BSI-045B and BSI-502, a novel bispecific antibody targeting TSLP and IL4R [1] - BSI-045B has shown a promising pharmacodynamic, safety, and efficacy profile in a Phase 2a trial for moderate to severe atopic dermatitis [1] - The agreement includes an upfront cash payment of over 40million,reimbursementfordevelopmentcosts,andpotentialmilestonepaymentsexceeding900 million [2][3] Financial Projections - The analyst estimates BSI-045B could generate approximately 1.3billioninrevenueby2035,witha352 to 7,indicatingapositiveshiftininvestorfocustowardsAclaris′immunologypipeline[4]−BTIGalsoupgradedAclarisfromNeutraltoBuy,settingapricetargetof8 [7] - Following these upgrades, ACRS stock experienced a significant increase of 55.60%, reaching $4.88 [8]