Illumina(ILMN) Prnewswire·2025-01-07 14:15Core Product Updates - The single-flow-cell NovaSeq X Sequencing System offers high-quality flow cells and speed at a more accessible cost for labs with lower volume, shipping began in December [1] - The NovaSeq X Series software v1 3 upgrade enhances sequencing performance and data quality, with new NovaSeq X 25B 100- and 200-cycle kits also shipping in December [1] - The NovaSeq X Series is Illumina's most rapidly adopted and utilized high-throughput sequencing platform to date [1] Customer Feedback on Software Upgrade - The v1 3 software upgrade improves sequencing accuracy, yield, and reduces PhiX dependency, leading to more usable data per run [3] - Génome Québec reported a significant leap in data quality across various library types, with increased yield and optimized handling of low-diversity libraries [4] - Broad Clinical Labs observed significant high-quality data yield increases in early testing of the v1 3 update on their NovaSeq X Plus fleet [4] - University Medical Center Utrecht noted a decisive development in transitioning from whole-exome-based to whole-genome-based analysis with the v1 3 update [4] New Kits and Applications - The new 25B 100-cycle and 200-cycle kits for the NovaSeq X Series are optimized for counting applications and other assays at scale, offering shorter turnaround times and cost-effective runs [5] - The 25B kits address the evolving needs of clinical specialty labs, academic core labs, and service providers by providing flexibility in run sizes and cycle counts [5] - The NovaSeq X 25B kits are compatible with Illumina Single-Cell Prep, enabling efficient, affordable, and accurate workflows for large-scale single-cell analysis projects [9] Illumina Single-Cell Prep - Illumina Single-Cell Prep, formerly Fluent PipSeq V, is now available and shipping, offering broad compatibility across Illumina's NGS platform portfolio [6] - The technology removes barriers and limitations of current methods, enabling scalability of experiments from hundreds to millions of cells with low equipment cost and high sensitivity [6][7] - Illumina Single-Cell Prep provides streamlined bioinformatics workflows, streaming data directly into automated DRAGEN analysis in Illumina's informatics cloud solutions [9] Industry Impact and Innovation - Illumina's focus on innovation has established it as a global leader in DNA sequencing and array-based technologies, serving customers in research, clinical, and applied markets [11] - The company's products are used in life sciences, oncology, reproductive health, agriculture, and other emerging segments [11] - Early access data presented at the American Society of Human Genetics meeting highlighted the sequencing of challenging cell types, such as astrocytes and brain tissue, with innovative technology [8]