Core Insights - Bionano Genomics published a case study demonstrating the successful application of optical genome mapping (OGM) in preimplantation genetic testing for structural rearrangements (PGT-SR), leading to a viable pregnancy and the birth of a healthy baby after years of recurrent pregnancy loss (RPL) experienced by the couple [1][2][3] Group 1: Case Study Details - The couple's RPL was attributed to complex chromosomal rearrangements (CCRs) in the male partner, which were identified using OGM, revealing previously undetected issues that traditional cytogenetic methods missed [2][7] - The OGM findings informed the selection of the most viable embryo, resulting in a successful pregnancy confirmed by prenatal testing that showed a normal karyotype [2][3] Group 2: Company Overview - Bionano Genomics specializes in genome analysis solutions, aiming to transform genomic understanding through OGM, diagnostic services, and software [4] - The company provides OGM solutions applicable across various research fields and offers a platform-agnostic genome analysis software solution, along with nucleic acid extraction and purification technologies [4] Group 3: Industry Impact - The case study suggests that OGM could significantly aid individuals facing infertility or RPL, which affects millions globally, indicating a potential breakthrough in reproductive health [3]
Bionano Announces Use of OGM in Preimplantation Genetic Testing as Part of Successful Live Birth to a Couple Experiencing Recurrent Pregnancy Loss