Core Insights - ICON plc (ICLR) reported fourth-quarter 2024 adjusted earnings per share (EPS) of 3.43,adecreaseof0.93.16, reflecting a 21.5% increase from the previous year, with full-year 2024 EPS reaching 14.00,up9.52.04 billion, and on a constant currency basis, the decline was 1.6%, although this figure exceeded the Zacks Consensus Estimate by 0.3% [3] - For the full year 2024, revenues amounted to 8.28billion,representinga2599.4 million, with gross margin contracting by 67 basis points to 29.4% [5] - Selling, general, and administrative expenses fell by 22.6% to 151.4million,whileadjustedoperatingincomeincreasedby5.4447.9 million, leading to an adjusted operating margin expansion of 138 basis points to 21.9% [5] Cash Position - At the end of 2024, ICON had cash and cash equivalents of 538.8million,upfrom378.1 million at the end of 2023, with a net debt balance of 2.9billion[6]−Cumulativecashflowfromoperatingactivitieswas1.29 billion, compared to 1.16billionintheprioryear[6]2025Guidance−Thecompanyreaffirmeditsfinancialguidancefor2025,expectingrevenuesintherangeof8.05 billion to 8.65billion,withtheZacksConsensusEstimateat8.33 billion [8] - Adjusted EPS is anticipated to be between 13.00and15.00, with the Zacks Consensus Estimate at $14.08 [8] Overall Performance - ICON's fourth-quarter results exceeded expectations for both earnings and revenues, with a sequential increase in gross business wins indicating a positive demand environment in the large pharma and biotech sectors [10] - Despite the positive performance, the contraction in gross margins is noted as a concern [11]