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Kiniksa Pharmaceuticals Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Portfolio Execution
KNSAKiniksa(KNSA) Newsfilter·2025-02-25 12:30

Core Insights - Kiniksa Pharmaceuticals reported strong sales growth for ARCALYST, achieving 417.0millioninnetproductrevenueforthefullyear2024,a79417.0 million in net product revenue for the full year 2024, a 79% increase year-over-year [2][10] - The company expects ARCALYST net product revenue to reach between 560 million and 580millionin2025[2][10]KiniksaplanstodiscontinuethedevelopmentofabiprubartinSjo¨grensDiseaseandfocusoncardiovascularindications[2][7]FinancialPerformanceTotalrevenueforQ42024was580 million in 2025 [2][10] - Kiniksa plans to discontinue the development of abiprubart in Sjögren's Disease and focus on cardiovascular indications [2][7] Financial Performance - Total revenue for Q4 2024 was 122.5 million, compared to 83.4millioninQ42023[10][25]Fullyear2024totalrevenuewas83.4 million in Q4 2023 [10][25] - Full year 2024 total revenue was 423.2 million, up from 270.3millionin2023[10][25]ThenetlossforQ42024was270.3 million in 2023 [10][25] - The net loss for Q4 2024 was 8.9 million, compared to a net income of 25.2millioninQ42023[10][25]Forthefullyear2024,thenetlosswas25.2 million in Q4 2023 [10][25] - For the full year 2024, the net loss was 43.2 million, compared to a net income of $14.1 million in 2023 [10][25] Product Development - Kiniksa is advancing KPL-387 for recurrent pericarditis, with a Phase 2/3 clinical trial expected to start in mid-2025 [2][8][10] - KPL-387 aims to provide a single monthly subcutaneous injection option for patients [2][7] - KPL-1161 is also being developed with a target profile of quarterly subcutaneous dosing [7][9] Market Position - Since the launch of ARCALYST, over 2,850 prescribers have written prescriptions for recurrent pericarditis [7] - As of Q4 2024, approximately 13% of the target 14,000 multiple-recurrence patients were actively on ARCALYST treatment [7]