Core Insights - COSCIENS Biopharma has repositioned itself as a pure-play natural-based product company following a strategic review and pipeline prioritization [1][3] - The company reported a revenue increase of 35.2% year-over-year, with total revenues of 9.6millionfortheyearendedDecember31,2024,comparedto7.1 million in 2023 [1][16] - The company ended the quarter with 16.4millionincashandcashequivalents[1][11]FinancialPerformance−ForQ42024,COSCIENSreportedaconsolidatednetlossof6.7 million, or 2.15losspershare,comparedtoanetlossof1.6 million, or 0.85losspershareinQ42023[12]−TotalrevenueforQ42024was3.3 million, an increase from 1.2millioninQ42023,primarilydrivenbyincreasedsalesofAvenanthramidesandBetaGlucan[13]−TotaloperatingexpensesforQ42024were8.4 million, up from 2.2millioninQ42023,duetohigherresearchanddevelopmentcostsandimpairmentexpenses[14]YearlyOverview−Forthefullyear2024,theconsolidatednetlosswas15.3 million, or 5.93losspershare,comparedtoanetlossof3.5 million, or 1.89losspersharein2023[15]−Totalrevenuefortheyearwas9.6 million, an increase of 2.4millionfrom7.1 million in 2023, attributed to higher sales of Avenanthramides and Beta Glucan [16] - Total operating expenses for the year were 23.0million,significantlyhigherthan7.5 million in 2023, driven by increased research and development and impairment expenses [18] Development Projects - The company has launched a new website for its JuventeDC product line, enhancing its online presence [5] - Avenanthramides Tablets are in clinical development, with successful Phase 1 results and a Phase 2a clinical efficacy study launched [7] - The Oat Beta Glucan Chewable Bar is set for commercial launch in H2 2025, while the Yeast Beta Glucan Powder is being finalized for commercialization as an immune booster [8] Strategic Direction - Following the negative results of the Phase 3 DETECT-Trial for macimorelin, the company has ceased investment in related pre-clinical programs and is exploring strategic options for this asset [3] - The company aims to reduce the cash burn rate while advancing promising programs from its legacy organizations [2] - COSCIENS is focused on leveraging its proprietary extraction technology to develop active ingredients from renewable plant resources for its product portfolio [23]