破解给药难题 科研团队研发出器官“创可贴”

Core Viewpoint - The research team from Beijing University of Aeronautics and Astronautics and Peking University has developed an "intelligent band-aid" electronic patch that enables precise and rapid drug delivery, addressing the challenges of traditional drug delivery methods [1][3]. Group 1: Technology and Innovation - The electronic patch is designed with a three-dimensional structure comprising nano-holes, micro-channels, and micro-electrodes, allowing for wireless power supply and safe perforation of cell membranes at low voltage [3]. - The patch facilitates point-to-point drug delivery by creating a high electric field strength within the nano-holes, effectively acting as a "highway" for drug transport [3]. Group 2: Clinical Results - In experiments with mice suffering from acute liver injury, the patch treatment group achieved a 100% survival rate over seven days, while the traditional treatment group had a 40% mortality rate [3]. - Pathological analysis indicated that the patch treatment group showed smooth and complete recovery of liver damage without inflammation or fibrosis, outperforming other treatment methods [3]. Group 3: Future Applications - The research findings have already been applied in fields such as medical aesthetics and skin wound repair, with potential future applications in treating major diseases like cancer and trauma [3].