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Pfizer Stock Up 5% Following Q1 Results: Time to Buy, Sell or Hold?
PFEPfizer(PFE) ZACKS·2025-05-05 13:11

Core Viewpoint - Pfizer's stock has seen a 5% increase following its first-quarter earnings report, which showed earnings growth but a decline in sales, primarily due to lower revenues from key products and the impact of Medicare Part D redesign [1][2][24]. Financial Performance - Pfizer reported earnings of 92 cents per share, a 12% increase year-over-year, while revenues declined by 6% on an operational basis [1]. - The company maintains its revenue outlook for 2025, projecting total revenues between 61.0billionand61.0 billion and 64.0 billion, with earnings expected in the range of 2.80to2.80 to 3.00 per share [2]. - The stock has declined 7.3% year-to-date, underperforming the industry, which has increased by 2.4% [15][17]. Product Sales and Market Trends - Sales of COVID-related products, Comirnaty and Paxlovid, are projected to drop to around 11billionin2024from11 billion in 2024 from 56.7 billion in 2022, with similar expectations for 2025 [5]. - Non-COVID operational revenues improved in 2024, driven by key products like Vyndaqel, Padcev, and newly acquired products from Seagen [6][7]. Oncology Segment - Pfizer has a strong position in oncology, with a 7% growth in oncology revenues in the first quarter of 2025, supported by drugs like Xtandi and Padcev [8][9]. - The acquisition of Seagen has further strengthened Pfizer's oncology portfolio, with several candidates entering late-stage development [8][9]. Challenges and Headwinds - Pfizer anticipates a moderate negative impact on revenues from the loss of exclusivity for several key products in 2025, with significant effects expected from 2026 to 2030 [11]. - The company expects an unfavorable impact of approximately 1billionfromtheMedicarePartDredesignundertheInflationReductionAct,particularlyaffectinghigherpriceddrugs[12].Pfizerhasfacedsetbacks,includingthediscontinuationoftheGLP1Ragonistdanuglipronduetosafetyconcerns[13].StrategicOutlookPfizerisfocusedoncostreductionsandinternalrestructuring,aimingforsavingsof1 billion from the Medicare Part D redesign under the Inflation Reduction Act, particularly affecting higher-priced drugs [12]. - Pfizer has faced setbacks, including the discontinuation of the GLP-1R agonist danuglipron due to safety concerns [13]. Strategic Outlook - Pfizer is focused on cost reductions and internal restructuring, aiming for savings of 7.7 billion by the end of 2027, which should support profit growth [25]. - The company returned $2.4 billion to shareholders through dividends in the first quarter of 2025, with a dividend yield of around 7.1% [26]. - Despite challenges, Pfizer's diversified portfolio and new growth prospects position it well for long-term gains, making it attractive for value and income investors [24][28].