Core Viewpoint - Myriad Genetics, Inc. reported a narrower adjusted loss in Q1 2025 compared to the previous year, but total revenues fell short of expectations and decreased year-over-year, leading to a significant drop in share price after the announcement [1][3][10]. Financial Performance - The adjusted loss per share was 3 cents, which was 40% better than the Zacks Consensus Estimate, while the GAAP EPS remained flat compared to a loss of 29 cents in the prior year [1][2]. - Total revenues decreased by 3.1% year-over-year to 195.9million,missingtheZacksConsensusEstimateby286.3 million [4]. - Pharmacogenomics testing revenues decreased by 20% year-over-year to 31million[4].−TumorProfilingtestingrevenuesdeclinedby529.3 million [4]. - Prenatal testing revenues increased by 11% year-over-year to 49.3million[4].MarginandExpenseAnalysis−Grossmarginimprovedby45basispointsto68.527.5 million, while SG&A expenses slightly decreased by 0.3% to 69million[5].−Theadjustedoperatinglosswas29 million, compared to a loss of 27.9millioninthepreviousyear[5].FinancialPosition−AttheendofQ12025,cashandcashequivalentswere91.8 million, down from 102.4millionattheendofQ42024[6].−Long−termdebtincreasedto59.3 million from 39.6millionattheendofQ42024[6].−Cumulativenetcashoutflowfromoperatingactivitieswas16.3 million, an improvement from 18.6millionintheprioryear[6].GuidanceandOutlook−Thecompanyrevisedits2025revenueguidancetoarangeof807-823million,downfromthepreviousestimateof840-$860 million, reflecting challenges in the pharmacogenomics and hereditary cancer testing segments [7]. - Adjusted EPS guidance was also lowered to a loss of 2 cents to earnings of 2 cents, compared to the previous range of 7-11 cents [8]. Business Developments - The decline in GeneSight revenues was attributed to changes in UnitedHealthcare's coverage policy and a reallocation of marketing spend [10]. - The hereditary business faced challenges due to slower-than-expected electronic medical record integrations [10]. - Positive developments included growth in Prenatal testing and the upcoming commercial launch of an AI-driven prostate cancer test in partnership with PATHOMIQ by the end of 2025 [11].