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颠覆传统!癌症治疗或迎来“无手术”时代

Group 1 - Traditional belief that "only surgical removal can cure tumors" is being challenged by new research [1] - A study published in JAMA Oncology shows that for HER2-positive or triple-negative breast cancer patients achieving pathological complete response (pCR) after neoadjuvant systemic therapy (NST), radiation therapy alone resulted in a 0% recurrence rate of the same-side breast tumor over five years, with 100% disease-free survival and overall survival rates [1] - This research indicates that radiation therapy can replace surgery for selected pCR patients, potentially changing future breast cancer treatment paradigms [1] Group 2 - Radiation therapy has become one of the three mainstays of cancer treatment alongside surgery and chemotherapy, with advancements in precision radiation technology allowing for targeted destruction of cancer cells [3] - Proton therapy, leveraging the "Bragg peak" effect, minimizes damage to normal tissues while effectively targeting cancer cells, emerging as a leading edge in radiation therapy [3] - Clinical practices from companies like Meizhong Jiahe (02453.HK) demonstrate the unique advantages of proton therapy in controlling tumors and reducing side effects compared to conventional photon therapy [3] Group 3 - Proton therapy offers hope for patients who cannot undergo surgery, with successful case studies showing significant tumor reduction and minimal side effects [4] - A patient with recurrent esophageal cancer and liver cancer underwent seven sessions of proton therapy without significant discomfort or traditional side effects, indicating the treatment's effectiveness [4] - Pediatric and elderly patients have also shown positive outcomes with proton therapy, highlighting its potential across different demographics [4] Group 4 - Proton therapy demonstrates significant potential in cancer treatment, with clinical results from institutions like Guangzhou Taihe Cancer Hospital providing new hope for patients [5] - As technology continues to evolve, more cancer patients may benefit from advanced radiation techniques, potentially leading to a future where "surgery-free" cancer cures become a reality [5]