Group 1 - The core point of the news is that President Trump signed an executive order aimed at reducing prescription drug prices in the U.S. to align with international standards, targeting a price reduction of 30% to 80% [1][3] - The U.S. pharmaceutical market is the largest globally, with American brand drug prices being over three times higher than those in other countries, despite the U.S. accounting for only 5% of the global population but bearing approximately 75% of global pharmaceutical profits [3][4] - Several Chinese innovative pharmaceutical companies, such as BeiGene and Junshi Biosciences, have successfully launched products in the U.S. market, with significant price disparities between the U.S. and China for their drugs [3] Group 2 - The implementation of Trump's drug pricing initiative faces uncertainty due to the existing U.S. laws that prohibit direct negotiations between the government and pharmaceutical companies, and the limited number of drugs eligible for negotiation each year [4] - The majority of U.S. drug spending is covered by commercial insurance, which stimulates pharmaceutical innovation and contributes to the economic growth of the industry [3][4] - The potential impact of the price reduction policy on the global innovative drug industry could be significant, as it may lead to a drastic contraction of the U.S. market size if Chinese prices are included in the U.S. reference pricing [3]