
Core Insights - Cognition Therapeutics, Inc. has released its tenth episode of the Conversations video podcast, focusing on the lived experiences of caregivers for patients with Lewy body dementia [1][2] - The podcast features insights from caregivers and physician experts involved in Cognition's Phase 2 'SHIMMER' study, discussing the challenges and symptoms associated with dementia with Lewy bodies (DLB) [2] Company Overview - Cognition Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing small molecule therapeutics for age-related neurodegenerative disorders [8] - The company is currently investigating its lead candidate, zervimesine (CT1812), in clinical programs for DLB and Alzheimer's disease [8][11] SHIMMER Study Details - The SHIMMER study is a Phase 2 clinical trial that enrolled 130 adults with mild-to-moderate DLB, randomized to receive either zervimesine or placebo for six months [6] - The study utilized various assessment tools, including the Neuropsychiatric Inventory and the Montreal Cognitive Assessment, to measure cognitive performance and symptoms [6] - The SHIMMER study received approximately $30 million in funding from the National Institute on Aging and was presented at the International Lewy Body Dementia Conference in January 2025 [7]